CREATININE CLEARANCE
| Item | Value | ||||
|---|---|---|---|---|---|
| Available Stat? | No | ||||
| Test code | CCLR | ||||
| Performed by? | Chemistry | ||||
| Sendout? | no | ||||
| Price range | $$ | ||||
| In House Availability | 7 days | ||||
| Interpretation | Low creatinine clearance indicates decreased glomerular filtration as with decreased renal plasma flow (prerenal), glomerulonephritis, and obstructive nephropathies. Kidney injury, as with shock and drugs (aminoglycosides, mercurials, amphotericin, and others) will decrease creatinine clearance. | ||||
| Container type | gel tube | ||||
| Amount to Collect | 3 mL | ||||
| Collection Instructions | Refrigerate urine during collection. Serum should be collected within 24 hours of urine specimen. |
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| Sample type | Clotted Blood | ||||
| Special instructions | Start 12- or 24-hour urine collection on the evening prior to drawing of blood sample. At the end of the 12- or 24-hour urine collection, draw blood specimen for creatinine. Send BOTH urine and blood to the lab. Patient's height and weight (inches, pounds) MUST accompany specimens, so correction of creatinine clearance to 1.73 m2 can be calculated.
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| Additional information | INDICATIONS: Monitor renal function (glomerular filtration rate). | ||||
| References | 1. Bayer(TM) Clinical Methods Creatinine (12) B01-4126-01 Advia 1650 Operator's Guide. PN 073-5001-09. Last accessed June 2003. Siemens Medical Solutions Diagnostics, Malvern, PA. 2. Duarte, CG and Preuss, HG. Assessment of Renal Function: Glomerular and Tubular. Clin Lab Med. 1993. 13:33-52. 3. Lake, DR et al.: Validity of Creatinine Clearance Estimates in the Assessment of Renal Function. Clin Pharmacol Ther. 1990. 48:503-8. 4. Van Lente, F and Suit, P. Assessment of Renal Function by Serum Creatinine and Creatinine Clearance: Glomerular Filtration Estimated by Four Procedures. Clin Chem. 1989. 35: 2326-30. |
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| CPT coding | 82575 |
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| Last Updated | 6/13/2013 11:08:50 AM |