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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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Item Value
Available Stat? No
Test code LDL
Performed by? Chemistry
Sendout? no
Price range $
In House Availability 7 days
Interpretation LDL Cholesterol on fasting specimens is calculated using the following formula:
LDL Cholesterol = Total cholesterol - (HDL Cholesterol + Triglycerides/5)
This calculation is not valid and performed for specimens having triglyceride > 400 mg/dL or < 40 mg/dL.

The current recommendations for the levels of the various forms of cholesterol in adults are as follows:

LDL Cholesterol mg/dL mmol/L
Optimal* < 100 < 2.59
Near or Above Optimal 100-129 2.59-3.34
Borderline High 130-159 3.36-4.11
High 160-189 4.14-4.89
Very High ≥ 190 ≥ 4.92

* < 70 mg/dL for high-risk cardiovascular disease patients (5)
Synonyms LDL, Cholesterol;Lipid Panel (CHOL, HDL, LDL, TRIG);
References 1. McManus, B.M.: Arch Pathol Lab Med, 110:469-71, 1986.

2. National Cholesterol Education Panel, Lipid Metabolism Branch, Division Heart, Lung, and Blood Institute. US Dept of Health and Human Services, Public Health Services, National Institutes of Health Bethesda, MD, JAMA 2001:285:2486-97.

3. Naito, H.K.: Clin Chem, 34/2:444-9, 1988.

4. Report of the National Education Program Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults. Arch Pathol Lab Med, 448:36-69, 1988.

5. Grundy SM, et al. Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation 110: 227 - 239, 2004.
Last Updated 8/19/2009 1:18:16 PM
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