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CA 125

Item Value
Available Stat? No
Test code CA125
Performed by? Chemistry
Sendout? no
Price range $$$
In House Availability M, W, F
Principle The Siemens Centaur Assay is a two-site sandwich immunoassay using direct chemiluminometric technology utilizing two monoclonal mouse antibodies specific for CA 125.
Interpretation For in vitro diagnostic use in the quantitative, serial determination of CA 125 in human serum, and to aid in the management of patients with ovarian carcinoma using the Centaur System. The test is intended for use as an aid in monitoring patients previously treated for ovarian cancer. Serial testing for CA 125 on the serum of patients who are clinically free of disease should be used in conjunction with other clinical methods used for the early detection of cancer recurrence. The test is also intended for use as an aid in the management of ovarian cancer patients with metastatic disease by monitoring the progression or regression of disease in response to treatment. It is recommended that the Centaur CA 125 II assay be used under the order of a physician trained and experienced in the management of gynecological cancers. This assay is not intended for screening or diagnosis of ovarian cancer or for use on any other system.
Container type gold gel tube
Amount to Collect 2 mL
Sample type Blood
Normal range < 30 U/mL
Stability Serum is stable for 8 hours at 2-8°C, longer at -20°C
References 1. Jacobs I, Bast RC Jr.: The CA 125 tumour-associated antigen: a review of the literature, Hum Reprod 4:1-12, 1989.

2. Bast RC Jr, Xu FJ, Yu YH, et al: CA 125: the past and the future, Int J Biol Markers 13:179-187, 1998.

3. Shih IM, Sokoll LJ, Chan DW: Ovarian Cancer. In Diamandis EP, Fritsche HA, Lilja H, et al, editors: Tumor markers. Physiology, pathobiology, technology, and clinical applications, Washington, DC, 2002, AACC Press.
CPT coding 86304
Last Updated 10/16/2012 7:24:26 PM
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