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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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INHIBITOR SCREEN (MIXING STUDIES)

Item Value
Approval req'd? PRE-APPROVAL REQUIRED. M-F, 8 am-5 pm page (415) 443-0179. After hours, week ends, and holidays contact (415) 206-8590.
Available Stat? No
Test code MIXS (IPTT for PTT, IPT for PT)
Performed by? Hematology
Sendout? no
Price range $$
In House Availability Monday - Friday, 9 am through 3 pm.
Principle This test establishes whether a prolonged PT or APTT is due to a factor deficiency or to the presence of an inhibitor. The test plasma is mixed with an equal volume of normal plasma. Correction of the PT or APTT to normal suggests a factor deficiency (the normal plasma has supplied the deficient factor). Lack of correction suggests the presence of an inhibitor (the normal plasma has been inhibited from correcting the prolonged PT or APTT).
Interpretation Some coagulation defects are caused by inhibitors of specific factors, rather than by the lack of a factor.
Container type blue top tube
Amount to Collect 1.5 mL
Collection Instructions Please refer to the front of this section for instructions on collecting coagulation specimens.
Sample type Citrated plasma
Special instructions Indicate use of Anticoagulant Drugs on Requisition Slip.
Normal range negative
Synonyms Mixing Studies;
References Triplett, D. and Harms, C.S. Procedures for the Coagulation Laboratory. Chicago, IL: Am. Soc. of Clin. Path., 1982.
CPT coding 85732
Last Updated 4/27/2011 3:28:30 PM
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