UCSF Departments of Pathology and Laboratory Medicine | SFGH Lab Manual | Laboratory Test Database

INHIBITOR SCREEN (MIXING STUDIES)

Item	Value
Approval req'd?	PRE-APPROVAL REQUIRED. M-F, 8 am-5 pm page (415) 443-0179. After hours, week ends, and holidays contact (415) 206-8590.
Available Stat?	No
Test code	MIXS (IPTT for PTT, IPT for PT)
Performed by?	Hematology
Sendout?	no
Price range	$$
In House Availability	Monday - Friday, 9 am through 3 pm.
Principle	This test establishes whether a prolonged PT or APTT is due to a factor deficiency or to the presence of an inhibitor. The test plasma is mixed with an equal volume of normal plasma. Correction of the PT or APTT to normal suggests a factor deficiency (the normal plasma has supplied the deficient factor). Lack of correction suggests the presence of an inhibitor (the normal plasma has been inhibited from correcting the prolonged PT or APTT).
Interpretation	Some coagulation defects are caused by inhibitors of specific factors, rather than by the lack of a factor.
Container type	blue top tube
Amount to Collect	1.5 mL
Collection Instructions	Please refer to the front of this section for instructions on collecting coagulation specimens.
Sample type	Citrated plasma
Special instructions	Indicate use of Anticoagulant Drugs on Requisition Slip.
Normal range	negative
Synonyms	Mixing Studies;
References	Triplett, D. and Harms, C.S. Procedures for the Coagulation Laboratory. Chicago, IL: Am. Soc. of Clin. Path., 1982.
CPT coding	85732
Last Updated	4/27/2011 3:28:30 PM