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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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Item Value
Available Stat? No
Test code HBAG
Performed by? Chemistry
Sendout? no
Price range $$
In House Availability Daily, Mon - Fri
Principle Microparticle Chemiluminometric Immunoassay.
Interpretation A positive result with a negative hepatitis B core IgM antibody indicates either an early acute hepatitis B viral infection or chronic hepatitis B infection. A positive result for both hepatitis B surface antigen and hepatitis B core IgM antibody usually indicates a recent hepatitis B infection. The combination of a negative result for hepatitis B surface antigen and a positive result for hepatitis B Core IgM antibody indicates a resolving hepatitis B infection.

To diagnose the acute phase (symptomatic 2 - 12 weeks) of hepatitis B infection, this test should be ordered in conjunction with hepatitis B core IgM antibody. To diagnose chronic, active hepatitis B infection, this test should be ordered in conjunction with Hepatitis B surface antibody and total core antibody.

As of July, 2004, hepatitis B surface antigen results with a low signal-to-cutoff ratio (S/CO) will be confirmed with a neutralization assay, as per manufacturer's guidelines.
Container type gold top gel tube
Amount to Collect 2 mL
Sample type Blood
Normal range negative
Synonyms HBS-AG;
Stability 2 days at 2-8°C, 1 month at -20°C.
References 1. Advia Centaur Assay Manual, Siemens Medical Solutions Diagnostics, Malvern, PA. Pub# 07398830, Rev. D, 2005-05.

2. Delmonico, F.L., Snydman, D.R. Organ Donor Screening for Infectious diseases. Transplantation 65(5): 603-610 (1998).

3. Wolter, G., Kuijpers, L., Kacaki, J., Schuurs, AHWM. Solid-Phase Enzyme- immunoassay for Detection of Hepatitis B Surface Antigen. J. Clin. Pathol. 29(10): 873-879 (1976).

4. Centers for Disease Control. Update: Universal precautions for prevention and transmission of human immunodeficiency virus, hepatitis B virus and other bloodborne pathogens in healthcare settings. MMWR 37:377-82, 387-8 (1988).
CPT coding 87340
Last Updated 10/22/2012 6:26:03 PM
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