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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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Item Value
Approval req'd? no
Available Stat? No
Test code FECW
Performed by? Hematology
Sendout? no
Price range $
In House Availability 7 days a week, 24 hours
Principle Stools from patients with diarrhea are examined microscopically for leukocytes using Loeffler's Methylene Blue stain
Interpretation INTERPRETATION:

Positive: many leukocytes seen in many fields.

Negative: leukocytes rare or absent.

CLINICAL SIGNIFICANCE: Leukocytes are found in stools in the presence of infection with bacteria that invade the colonic mucosa (i.e., Salmonella, Shigella, Yersinia and invasive E. coli). Other disorders that may be associated with fecal leukocytes are ulcerative colitis and antibiotic associated colitis. Fecal leukocytes are usually absent in diarrhea secondary to toxigenic bacteria, parasites or virus.
Collection Instructions Must be performed on a fresh stool specimen within 24 hours. Test will not be performed on formed stool samples.
Sample type Stool
Normal range Negative: leukocytes rare or absent.
Synonyms Stool WBC (Leukocytes);
Causes for rejection for med stool samples
References 1. Harris et al.: "Fecal Leukocytes in Diarrheal Illness." Annals Internal Medicine, 76:697, 1972.

2. Bluth, MH et al.: Laboratory Diagnosis of Gastrointestinal and Pancreatic Disorders. In Clinical Diagnosis and Management by Laboratory Methods. 21st ed., W.B. Saunders, Philadelphia, 2007, p. 279-296.
CPT coding 89055
Last Updated 8/19/2009 1:21:18 PM
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