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Lab Manual for Moffitt-Long and Mount Zion

Lab Manual for SFGH

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Likelihood Ratios, by test


DESCRIPTION, by test DISEASE SENS SPEC LR+ LR- REF
Abd CT Pancreatitis, Acute  0.7 0.93 10 0.32 R
Abd US Acute cholecystitis  0.95 0.96 23.8 0.05
Abd US Common duct stone  0.3 0.92 3.8 0.76 R
Abd US Ureteral obstruction  0.98 0.9 9.8 0.02 R
Abd US  Abscess 0.96 0.95 19.2 0.04 R
Abdominal CT Abscess  0.95 0.9 9.5 0.06
Alk Phos elevation Liver mets  0.75 0.8 3.8 0.31
Amylase (2x nml) Pancreatitis, Acute  0.95 0.98 47.5 0.05 R
ANA Ab SLE  0.9 0.8 4.5 0.125
Anti-DNA Ab ( > 1:80 ) SLE  0.73 0.99 73 0.27
Bone films Osteomyelitis  0.5 0.91 5.6 0.55
Bone scan Breast Cancer  0.96 0.84 6 0.05
Bone scan Lung Cancer, metastatic  0.97 0.97 32 0.03
C. diff toxin assay C. diff colitis  0.98 0.95 19.6 0.02 R
CEA ( > 2.5 ng/ml ) Colon cancer - Stage A  0.28 0.83 1.6 0.87 R
CEA ( > 2.5 ng/ml ) Colon cancer - Stage D  0.84 0.83 4.9 0.19 R
CK-Mb Acute MI  0.97 0.97 32.3 0.03
Clinical breast exam Breast Cancer  0.35 0.9 3.8 0.69 R
CXR  Lung Cancer  0.6 0.96 15 0.42 R
CXR  Cardiomegaly  0.88 0.83 5.2 0.14
Dipstick Hematuria  0.95 0.85 6.4 0.06
Duplex ultrasound Carotid atherosclerosis  0.9 0.9 9 0.11
ECHO Endocarditis  0.37 0.96 9.3 0.66
ECHO LVH  0.92 0.95 18.4 0.08 R
ECHO Aortic Stenosis (critical) 0.91 0.65 2.6 0.14
ECHO  Regional wall motion abn.  0.95 0.89 8.6 0.06 R
ECHO  Valve abn 0.93 0.95 18.6 0.07
EKG, (serial) MI  0.68 0.99 68 0.32
EKG, (single)  MI 0.57 0.98 28.5 0.44
Endoscopy Ulcer          R
ESR ( >20 ) Endocarditis  0.93 0.96 23 0.07
ESR ( >20 ) PID  0.86 0.96 21.5 0.15
ESR ( >20 ) Temporal arteritis  0.99 0.96 24.8 0.01
ETT CAD in women  0.61 0.7 2.25 0.55
Exercise ECHO  CAD in women  0.86 0.79 4.29 0.18
Exercise EKG (1 mm depression) CAD  0.6 0.83 3.5 0.45 R
Exercise thallium  CAD in women  0.78 0.64 2.87 0.36
Ferritin ( <12 ) Iron def anemia  0.85 0.99 0.85 0.15
FEV <80% COPD (in middle-age pts)  0.27 0.9 2.7 0.81
Head CT Acute bleed  0.95 0.96 23.8 0.05 R
Head CT Ischemic stroke <24 hrs  0.61       R
Head CT SAH <24 hrs  0.97 0.95    
Head CT  Brain tumor  0.95 0.97 31.7 0.05 R
Head CT  Subdural hematoma, Chronic 0.93 0.94 15.5 0.07 R
HLA -B27 Reiters syndrome  0.75 0.92 9.4 0.27 R
KUB  Lg Bowel obstruction  1 0.9 10 0
LFTs ( AST>1000 ) Liver damage  0.28 0.99 28 0.73
Lipase  Pancreatitis, Acute  0.87 0.99 87 0.13 R
Mammogram  Breast Cancer  0.87 0.9 8.7 0.14 R
Renal scan  Renal Artery Stenosis 0.77 0.81 4.1 0.28 R
Transferrin ( <16.6 saturation ) Fe def anemia  0.96 0.7 3.2 0.06
UGI (double contrast) Ulcer, Duodenal 0.85 0.95 17 0.16 R
UGI (double contrast)  Ulcer, Gastric 0.85 0.95 17 0.16
UGI (single contrast) Ulcer, Duodenal 0.75 0.95 15 0.26 R


Last Updated on 2/3/99
Originally created by Michael Pignone, M.D. and Chris Phillips, M.D.
Ongoing updates by Mark Lu, M.D. and Enrique Terrazas, M.D.
Email: Enrique.Terrazas@ucsf.edu, Mark.Lu@va.gov

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