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Likelihood Ratios, by disease


DESCRIPTION, by disease TEST SENS SPEC LR+ LR- REF
Abscess Abd US 0.96 0.95 19.2 0.04 R
Abscess  Abdominal CT 0.95 0.9 9.5 0.06
Acute bleed  Head CT 0.95 0.96 23.8 0.05 R
Acute cholecystitis  Abd US 0.95 0.96 23.8 0.05
Acute MI  CK-Mb 0.97 0.97 32.3 0.03
Aortic Stenosis (critical) ECHO 0.91 0.65 2.6 0.14 R
Brain tumor  Head CT  0.95 0.97 31.7 0.05 R
Breast Cancer  Mammogram  0.87 0.9 8.7 0.14 R
Breast Cancer  Bone scan 0.96 0.84 6 0.05
Breast Cancer  Clinical breast exam 0.35 0.9 3.8 0.69 R
C. diff colitis  C. diff toxin assay 0.98 0.95 19.6 0.02 R
CAD  Exercise EKG (1 mm depression) 0.6 0.83 3.5 0.45 R
CAD in women  Exercise ECHO  0.86 0.79 4.29 0.18
CAD in women  Exercise thallium  0.78 0.64 2.87 0.36
CAD in women  ETT 0.61 0.7 2.25 0.55
Cardiomegaly  CXR  0.88 0.83 5.2 0.14
Carotid atherosclerosis  Duplex ultrasound 0.9 0.9 9 0.11
Colon cancer - Stage A  CEA ( > 2.5 ng/ml ) 0.28 0.83 1.6 0.87 R
Colon cancer - Stage D  CEA ( > 2.5 ng/ml ) 0.84 0.83 4.9 0.19 R
Common duct stone  Abd US 0.3 0.92 3.8 0.76 R
COPD (in middle-age pts)  FEV <80% 0.27 0.9 2.7 0.81
Endocarditis  ESR ( >20 ) 0.93 0.96 23 0.07
Endocarditis  ECHO 0.37 0.96 9.3 0.66
Fe def anemia  Transferrin ( <16.6 saturation ) 0.96 0.7 3.2 0.06
Hematuria  Dipstick 0.95 0.85 6.4 0.06
Iron def anemia  Ferritin ( <12 ) 0.85 0.99 0.85 0.15 R
Ischemic stroke <24 hrs  Head CT 0.61       R
Lg Bowel obstruction  KUB  1 0.9 10 0
Liver damage  LFTs ( AST>1000 ) 0.28 0.99 28 0.73
Liver mets  Alk Phos elevation 0.75 0.8 3.8 0.31
Lung Cancer, metastatic  Bone scan 0.97 0.97 32 0.03
Lung Cancer  CXR  0.6 0.96 15 0.42 R
LVH  ECHO 0.92 0.95 18.4 0.08 R
MI EKG, (single)  0.57 0.98 28.5 0.44
MI  EKG, (serial) 0.68 0.99 68 0.32
Osteomyelitis  Bone films 0.5 0.91 5.6 0.55
Pancreatitis, Acute  Abd CT 0.7 0.93 10 0.32 R
Pancreatitis, Acute  Amylase (2x nml) 0.95 0.98 47.5 0.05 R
Pancreatitis, Acute  Lipase  0.87 0.99 87 0.13 R
PID  ESR ( >20 ) 0.86 0.96 21.5 0.15
Regional wall motion abn.  ECHO  0.95 0.89 8.6 0.06 R
Reiters syndrome  HLA -B27 0.75 0.92 9.4 0.27 R
Renal Artery Stenosis Renal scan  0.77 0.81 4.1 0.28 R
SAH <24 hrs  Head CT 0.97 0.95    
SLE  ANA Ab 0.9 0.8 4.5 0.125
SLE  Anti-DNA Ab ( > 1:80 ) 0.73 0.99 73 0.27
Subdural hematoma, Chronic Head CT  0.93 0.94 15.5 0.07 R
Temporal arteritis  ESR ( >20 ) 0.99 0.96 24.8 0.01
Ulcer  Endoscopy         R
Ulcer, Duodenal UGI (double contrast) 0.85 0.95 17 0.16 R
Ulcer, Duodenal UGI (single contrast) 0.75 0.95 15 0.26 R
Ulcer, Gastric UGI (double contrast)  0.85 0.95 17 0.16
Ureteral obstruction  Abd US 0.98 0.9 9.8 0.02 R
Valve abn ECHO  0.93 0.95 18.6 0.07


Last Updated on 2/3/99
Originally created by Michael Pignone, M.D. and Chris Phillips, M.D.
Ongoing updates by Mark Lu, M.D. and Enrique Terrazas, M.D.
Email: Enrique.Terrazas@ucsf.edu, Mark.Lu@va.gov

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