UCSF Navigation Bar

UCSF Departments of Pathology & Laboratory Medicine Home Page

Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

Internal Resources

Click here for more information about laboratory operations and procedures

If you have additional questions regarding this test, please call: 415-353-1667

Search Our Test Menu

Valproic acid

Item Value
Test Update Information Valproic assay changed from the Abbott Axsym method to the Beckman DxC method on 09/20/2012.
Approval req'd? No
Available Stat? Yes
Test code VALP
Performed by Parnassus & Mission Bay Chemistry
In House Availability Test available 24 hours per day 7 days per week
Method Turbidimetric inhibition immunoassay (Beckman DxC800)
Collection Instructions Time to steady state: 2-3 days.

Collect trough samples 30 minutes before next dose.
Container type Gold top or Light Green top
Amount to Collect 1 mL blood
Sample type Serum or plasma
Preferred volume 0.5 mL serum or plasma
Min. Volume 0.2 mL serum or plasma
Units mg/L
Normal range
Therapeutic 50-125 mg/L

VPA therapeutic range of 50 - 125 mg/L was set based on recommendations in the literature and consultations with UCSF pharmacists and neurologists.
Source: Valproate: Drug information copyright 1978-2012, Lexicomp, Inc. Accessed at UpToDate www.uptodate.com August 2012.
Critical value > 150 mg/L
Synonyms Depakene; Valproate; Depakote
Stability Room temperature 8 hours, refrigerated 2 days, frozen at -20C 1 week
Turn around times Stat 1 hour, Routine 4 hours
Additional information Click here for: A Guide on Drug Level Monitoring
CPT coding 80164
LOINC code 4086-5
Last Updated 6/21/2016 12:03:23
Entry Number 973
UCSF home page UCSF home page About UCSF Search UCSF UCSF Medical Center