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Toxoplasma gondii Antibody, IgM, CSF

Item Value
Approval req'd? No
Available Stat? No
Test code TXCM and TXCG
Performed by Quest
Sendout? Yes
Method EIA
Collection Instructions Specimen label must contain the date the sample was collected and the legible name of the person who collected the sample.
Container type CSF tube or sterile collection tube
Amount to Collect See preferred volume
Sample type CSF
Preferred volume 1 mL CSF
Min. Volume 0.1 mL CSF
Processing notes Refrigerate. Order Quest test # 10485X
Normal range
Negative < 0.90
Equivocal 0.9-1.09
Positive ≥ 1.10
Turn around times Test run Monday-Friday. Turnaround time: 2-4 days.
Additional information This test is always run in conjunction with a test for IgG Antibody.

The FDA recommends that IgM assays only be performed in conjunction with an IgG Antibody test. Equivocal results may be clarified by repeating the test after an additional week or more has passed. Because IgM antibody may persist for more than a year after acute infection, IgM assay is most reliable in excluding recent primary infection, except in the earliest stages or in rare neonates who do not have an early IgM response, in whom additional testing may be needed. IgM is not usually elevated in disease due to reactivation of latent infection, such as chronic chorioretinitis or encephalitis in immunosuppressed patients with AIDS or lymphoma. The diagnosis of acute or recent Toxoplasma gondii infection should not be based on one IgM serology result. It is suggested that a positive result be confirmed by an alternate method.
CPT coding 86778-90, 86777-90
Last Updated 6/21/2016 12:28:48
Entry Number 937
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