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Toxoplasma gondii Antibody, IgG & IgM
|In House Availability||Once a week (usually on Wednesday, day shift)|
|Method||Enzyme-Linked Immunosorbent Assay (ELISA)|
|Collection Instructions||Avoid hemolysis|
|Container type||Gold top|
|Amount to Collect||2 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.5 mL serum|
|UCSF Rejection Criteria||Grossly hemolyzed, lipemic or icteric samples|
|Processing notes||Freeze at -20C|
|Turn around times||1-8 days|
|Additional information||The FDA recommends that IgM assays only be performed in conjunction with an IgG Antibody test. Equivocal results may be clarified by repeating the test after an additional week or more has passed. Because IgM antibody may persist for more than a year after acute infection, IgM assay is most reliable in excluding recent primary infection, except in the earliest stages or in rare neonates who do not have an early IgM response, in whom additional testing may be needed.
IgM is not usually elevated in disease due to reactivation of latent infection, such as chronic chorioretinitis or encephalitis in immunosuppressed patients with AIDS or lymphoma. The diagnosis of acute or recent Toxoplasma gondii infection should not be based on one IgM serology result. It is suggested that a positive result be confirmed by an alternate method.
|Last Updated||4/20/2016 5:53:10 PM|