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Toxoplasma gondii Antibody, IgG & IgM

Item Value
Approval req'd? No
Available Stat? No
Test code TOGM
Performed by Immunology
In House Availability Tuesday (day shift)
Method Chemiluminescent immunoassay
Container type Gold top
Amount to Collect 1 mL blood
Sample type Serum
Preferred volume 0.5 mL serum
Processing notes Freeze at -20C
Normal range Negative
Synonyms TORCH Antibodies
Turn around times 1-8 days
Additional information The FDA recommends that IgM assays only be performed in conjunction with an IgG Antibody test. Equivocal results may be clarified by repeating the test after an additional week or more has passed. Because IgM antibody may persist for more than a year after acute infection, IgM assay is most reliable in excluding recent primary infection, except in the earliest stages or in rare neonates who do not have an early IgM response, in whom additional testing may be needed.

IgM is not usually elevated in disease due to reactivation of latent infection, such as chronic chorioretinitis or encephalitis in immunosuppressed patients with AIDS or lymphoma. The diagnosis of acute or recent Toxoplasma gondii infection should not be based on one IgM serology result. It is suggested that a positive result be confirmed by an alternate method.

Human anti-mouse antibodies (HAMA) or heterophile antibodies may be present in samples from individuals exposed to mouse or animal immunoglobulins from natural sources or as part of disease therapies. These antibodies may interfere with the Centaur Toxoplasma M assay and may give falsely positive or falsely negative results. These samples should not be tested.
LOINC code 25542-2
Last Updated 12/20/2013 11:27:28 AM
Entry Number 936
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