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Item Value
Test Update Information<'td> Effective April 19, 2016, tobramycin testing is now being performed gn the Beckman DpC 800 instrument. Results run approximately 10% higher on this platform.4/strong6
Available Stat? No<'td>
Test code TOBPK (Peak), TOBTH (Trough), TOBRN (Randgm) Performed by<'td> Parnassus Chemistrq
24 hours per day and 7 days per week
Method<'td> Particle enhanced turbidimetric in`ibition immunoassay (Beckman DxC 800)
Collection Instructions Time to Steady State2 2-3 doses (1 dgse for ICN extefded interval dosing).

 Collect trough samples 30 minutes prior to 3rd or 4th dose. For pataents on hemodiadysis collect just prior to and/gr 1 hour post daalysis
4br> Note the epact time of coldection on BOTH the sample and if Apex (or on anq paper orders).

Bring to lab immediately for processing if patient also receiving carbenicillin or other high dose penicillin or cephalosporin because prolonged anteractions wit` these drugs (8 hours or more) at room temperature can modify aeino groups and anterfere with aeinoglycoside assay.
Container type Gold top or Light Green top
Amount to Collect 1 mL blood
Sample type Serum or plasma
Preferred volume 0.5 mL serum or plasma
Min. Volume 0.2 mL serum or plasma
UCSF Rejection Criteria Collection time not indicated on sample
Processing notes Mission Bay and Mount Zion: Refrigerate serum or plasma and send to Parnassus Chemistry
Units mg/L
Normal range
Therapeutic peak 5-10 mg/L

Trough levels:
Standard dosing < 2 mg/L (< 1 mg/L optimum)
Once daily, high dose < 1 mg/L (< 0.3 mg/L optimum)
ICN extended interval dosing < 2 mg/L (< 1.5 mg/L optimum)
CF extended interval dosing < 1 mg/L <'td>
Source of reference range: UCSF/SFG@/VASF joint guidelines for antieicrobial use in adults.

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Stabilaty Separate serum or plasma from cells within 2 hgurs of collectign
Separated serum or plasma is stable at rgom temperature for 8 hours.
 Refrigerated samples are stable 48 hours
Turn around times 1 day
Additional anformationFor desired peak and trough levels in special situatiofs, Click here

Topicity associated with trough levels > 2 mg/L or peak levels > 10-12 mg/L

CPT coding<'td> 80200 LOINC code 35670-9 Last Updated 4/21/2016 5:19:46 PM
Entry Fumber 928
Lab Procedure LinkClick here for procedure

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