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Thyroid Stimulating Immunoglobulin
|Clinical Questions||Does my patient have autoimmune thyroiditis?|
|Test group||Thyroid tests|
|Container type||Gold top, Red top|
|Amount to Collect||4 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.2 mL serum|
|UCSF Rejection Criteria||Gross hemolysis, gross lipemia, grossly icteric samples|
|Processing notes||Freeze at -20C. Order Quest # 30551|
|Ref Lab Rejection Criteria||Gross hemolysis, gross lipemia, grossly icteric samples|
|Units||% of baseline|
|Normal range||Negative <140% of baseline (See Additional information)|
|Synonyms||TSI; TSH receptor antibodies; Human Thyroid Stimulator (HTS); Long-Acting Thyroid Stimulator (LATS); Thyroid-Stimulating Antibody (TSAb)|
|Stability||Refrigerated 3 weeks, frozen at -20C 2 months.|
|Turn around times||Set up 5 days per week. Turnaround 3-6 days|
|Additional information||A positive result is one in which the Specimen to Reference Ratio (%) (SSR%) is >140% of the Reference Control.
Thyroid stimulating immunoglobulins (TSI) can engage the TSH receptors resulting in hyperthyroidism in Graves' disease patients.
TSI levels can be useful in monitoring the clinical outcome of Graves' disease as well as assessing the potential for hyperthyroidism from maternal-fetal transfer.
NOTE: A serum TSH level greater than 350 µIU/mL can interfere with the TSI bioassay and potentially give false positive results.
|Last Updated||11/20/2010 11:26:30 AM|