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|Clinical Questions||Does my patient have autoimmune thyroiditis?|
|Test group||Thyroid tests|
|In House Availability||Friday (day shift)|
|Container type||Gold top|
|Amount to Collect||2 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.5 mL serum|
|Processing notes||Stored frozen at -20C.|
|Synonyms||anti-TPO antibodies; anti-microsomal antibodies|
|Turn around times||1-8 days|
|Additional information||The results of this test should be used in conjunction with clinical findings and other laboratory data (such as TSH and thyroid hormone levels) to make a diagnosis of autoimmune thyroid disease (including Hashimoto's thyroiditis and Graves' Disease). Although anti-thyroperoxidase antibodies are a sensitive and specific indicator of autoimmune thyroid disease, a subset of normal individuals may have low level antibodies that may not have clinical significance resulting in a false positive test result. The Manufacturer's guidelines suggest that up to 4-5% of normal individuals may have a positive result with this assay.
The antibody reactivity previously ascribed to the thyroid microsomes is now recognized to be primarily directed against Thyroperoxidase, and is the antibody activity most commonly found in thyroid disease.
|Last Updated||2/19/2014 4:07:38 PM|