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DEACTIVATED Thyroglobulin

Item Value
Approval req'd? No
Available Stat? No
Test code TGLB
Test group Thyroid tests
Performed by China Basin Chemistry
In House Availability Tuesday, Thursday (day shift)
Method Chemiluminescent immunometric
Container type Gold top
Amount to Collect 8 mL blood
Sample type Serum
Preferred volume 4 mL serum
Min. Volume 1 mL serum
Processing notes Freeze serum at -20C.
Units µg/L
Normal range 1.4-33.6 µg/L
Synonyms Tg
Turn around times 1-5 days
Additional information Each specimen is routinely tested for the presence of Anti-Thyroglobulin Antibodies (normally ≤ 20 IU/mL); antibody interferes with the assay and can give either falsely high or low results: test results must be interpreted with extreme caution in their presence.

Thyroglobulin levels are useful to assess the presence of residual papillary-follicular thyroid carcinoma. Increasing levels indicate recurrence or metastasis. Levels are not elevated in medullary or anaplastic thyroid carcinomas nor with small tumors, and are generally not useful as a screening test for thyroid cancer.

This protein may be elevated in hyperthyroidism and in Hashimoto's thyroiditis, but its measurement is superfluous for the diagnosis of these conditions.

In the DPC Immulite 2000 assay, the functional sensitivity defined as the lowest value that can be measured in thyroglobulin-negative antibody serum with a 20% coefficient of variation has been estimated to be 0.9 µg/L. Results below this level will be reported as < 0.9 µg/L
LOINC code 3013-0
Last Updated 3/19/2013 8:39:42 AM
Entry Number 919

If you have additional questions regarding this test, please call: 415-353-1667

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