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Lab Manual for Moffitt-Long and Mount Zion

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N-Telopeptide, random urine

Item Value
Approval req'd? No
Available Stat? No
Test code NTX
Performed by Quest
Sendout? Yes
Method Enhanced Chemiluminescence
Collection Instructions The preferred sample is a second void urine. have patient void first morning urine and collected second void.
Container type Urine cup
Amount to Collect Random urine
Sample type Random urine
Preferred volume 2 mL urine
Min. Volume 1 mL urine
UCSF Rejection Criteria Preserved or acidified sample.
Processing notes Aliquot 2 mL and freeze at -20C. Order Quest #36167X
Units nmol BCE/mmol creatinine (BCE = Bone Collagen Equivalents)
Normal range Pediatric:

0-6 months 2-32 nmol BCE/mmol creatinine
7-11 months 2-36 nmol BCE/mmol creatinine
1-2 years 2-128 nmol BCE/mmol creatinine
3-8 years 2-149 nmol BCE/mmol creatinine
9-12 years 2-183 nmol BCE/mmol creatinine
12-18 years male 20-370 nmol BCE/mmol creatinine
> 12 years female 20-320 nmol BCE/mmol creatinine


Premenopausal Females 4-64 nmol BCE/mmol creatinine


Males:
18-29 years 12-99 nmol BCE/mmol creatinine
30-59 years 9-60 nmol BCE/mmol creatinine
Synonyms Collagen-Crosslinked
Stability Room temperature 3 days, refrigerated 5 days, frozen at -20C 1 month
Turn around times Test run Tuesday-Sunday Turnaround time: 2-6 days.
Additional information This assay reflects breakdown of bone matrix by collagenase. A value within the premenopausal range does not exclude osteoporosis or the need for therapy.

Results are primarily of use in monitoring the
response to treatment. A decline of ≥ 30% following 6 months of estrogen replacement therapy is indicative of a positive therapeutic response in postmenopausal women and in 88% of women was associated with maintained or increased bone mineral density Ref: Chestnut CH et al. Amer J Med 1997;192:29
CPT coding 82523-90
Medical Necessity? Yes. Click here for more information
LOINC code 14115-0
Last Updated 3/24/2013 7:53:42 PM
Entry Number 889

If you have additional questions regarding this test, please call: 415-353-1667

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