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Sjogren's Antibodies

Item Value
Approval req'd? No
Available Stat? No
Test code SSAB
Performed by Immunology
In House Availability Wednesday (day shift)
Method EIA
Container type Gold top
Amount to Collect 1 mL blood
Sample type Serum
Preferred volume 0.5 mL serum
Processing notes Freeze at -20C
Units Units
Normal range anti-SSA and anti-SSB:

Negative < 20 Units
Weak Positive 20-39 Units Index
Moderate Positive 40-80 Units
Stron Positive > 80 Units
Synonyms anti-SSA; anti-SSB; anti-Ro; anti-La
Turn around times 2-9 days
Additional information Antibodies to SSA (Ro) are present in approximately 60-70% of patients with Sjogren's syndrome and 30-40% of patients with systemic lupus erythematosus (SLE). The presence of this autoantibody in pregnant women has been associated with development of neonatal congenital heart block and neonatal lupus. Antibodies to SSB (La) are found in approximately 60% of patients with
Sjogren's syndrome and 11-24% of patients with SLE.

Weak positive results may not have clinical significance. Clinical correlation is advised. Repeat testing may be considered, if clinically indicated.
LOINC code 33569-5
Last Updated 1/30/2013 12:09:55 PM
Entry Number 857
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