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Sjogren's Antibodies

Item Value
Approval req'd? No
Available Stat? No
Test code SSAB
Performed by Immunology
In House Availability Once a week (usually Tuesday day shift)
Method Chemiluminescent
Container type Gold top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.5 mL serum
UCSF Rejection Criteria Grossly hemolyzed, lipemic or icteric samples
Processing notes Freeze serum at -20C
Units Chemiluminescent Units (CU)
Normal range anti-SSA-Ro52, anti-SSA-Ro60 and anti-SSB:

Negative < 20 CU
Positive ≥ 20 CU

Turn around times 2-9 days
Additional information Antibodies to SSA (Ro) are present in approximately 60-70% of patients with Sjogren's syndrome and 30-40% of patients with systemic lupus erythematosus (SLE). The presence of this autoantibody in pregnant women has been associated with development of neonatal congenital heart block and neonatal lupus. Antibodies to SSB (La) are found in approximately 60% of patients with
Sjogren's syndrome and 11-24% of patients with SLE.

Clinical correlation is advised. Repeat testing may be considered, if clinically indicated.
CPT coding 86235 x3
LOINC code 33569-5
LDT or Mod FDA? No
Last Updated 3/29/2016 6:05:35 PM
Entry Number 857
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