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|Performed by||China Basin Chemistry|
|In House Availability||Daily (day shift)|
|Method||Abbott Architect Chemiluminescent Immunoassay|
|Collection Instructions||Time to steady state: 6-10 days
Trough samples should be collected no more than 30-60 minutes before next dose
|Container type||Lavender top|
|Amount to Collect||2 mL blood|
|Sample type||EDTA whole blood|
|Preferred volume||2 mL whole blood|
|Min. Volume||0.3 mL whole blood
Note: This volume does not allow for repeat testing if needed.
|Turn around times||For samples received by 1200 (Monday-Friday) and 1000 (weekends and holidays) the results will be available by 1600. Results for samples that miss the cut-off times will be available the following day.|
|Additional information||Sirolimus is an immunosuppresant drug used to prevent organ graft rejection. Therapeutic drug monitoring is used to optimize dose.
This method yields results approximately 20% higher than the Abbott IMx immunoassay due to improved extraction and recovery of sirolimus from whole blood samples. Information regarding cross reactivity of this assay with metabolites and other drugs can be found in the link to the Lab Procedure.
Click here for: A Guide on Drug Level Monitoring
|Last Updated||11/16/2014 7:07:25 PM|
|Lab Procedure Link||Click here for Procedure|