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Lab Manual for Moffitt-Long and Mount Zion

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Saccharomyces cerevisiae Antibody

Item Value
Approval req'd? No
Available Stat? No
Test code MOLT (Order in Apex as 'Miscellaneous Outside Lab Test' using the complete test name above)
Performed by Quest
Sendout? Yes
Container type Gold top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.5 mL serum
Processing notes Refrigerate serum, send in plastic tube, order #10295N for IgA and/or #10294N for IgG
Normal range
Additional information The presence of IgG or IgA antibodies against the mannan antigen of S. cerevisiae in patients with gastrointestinal complaints is
associated with a diagnosis of Crohn's disease. Although the specificity is relatively high (90-95%), the test may also be positive in small number of patients with gluten sensitive enteropathy, primary biliary cirrhosis, and Behcet's disease.

The sensitivity of the test is low (45-60%), therefore a negative test does not rule out the diagnosis.
Last Updated 2/20/2014 3:16:32 PM
Entry Number 839
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