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Protein, Total, Plasma / Serum

Item Value
Test Update Information Effective November 4, 2015 , the total protein reference range has been modified due to changing from serum to plasma as the preferred sample type. It is known that plasma total protein levels run about 0.3 g/dL higher than serum samples due to fibrinogen which has been verified by in house studies.
Approval req'd? No
Available Stat? No
Test code TP
Test group Total protein
Performed by Parnassus, Mission Bay & Mt. Zion Chemistry
In House Availability Test available 24 hours per day 7 days per week
Method Spectrophotometric (biuret)
Container type Light green top preferred, Gold top acceptable
Amount to Collect 1 mL blood
Click here for Microdetermination info
Sample type Plasma or serum
Preferred volume 0.5 mL plasma or serum
Min. Volume 0.2 mL plasma or serum
Click here for Microdetermination info
Units g/dL
Normal range
< 1 year 4.3 – 7.2 g/dL
1 year - 2 years 5.2- 7.7 g/dL
3 years - 5 years 5.6 - 8.0 g/dL
6 years- 9 years 6.5 - 8.6 g/dL
≥ 10 years 6.0- 8.4 g/dL

Normal ranges for children less than 10 years old adopted from Beckman Coulter's "Pediatric Reference Range Guidelines for Synchron Systems" Bulletin 9345 with the upper limits of normal adjusted for plasma specimens.

Normal range for adults: low end of 6.0 determined by testing 271 normal male and female UCSF blood donors and referenced by Beckman as the low end of adult recumbent patients. High end of 8.4 based on the Beckman Synchron upper limit of normal adjusted for plasma specimens.

Adult range used for children 10-18 years old. Adult range comparable to Beckman's range for age group 10-19 years (Bulletin 9345).
Synonyms TP
Stability Room temperature 8 hours, refrigerated 2 days, frozen at -20C 1 week
Turn around times 4 hours
Additional information Lipemia may artifactually decrease the result.
LOINC code 2885-2
Last Updated 7/24/2015 8:42:45 AM
Entry Number 791
Lab Procedure Link Click here for Procedure
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