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Primidone
| Item | Value |
|---|---|
| Approval req'd? | No |
| Available Stat? | No |
| Test code | PRIM |
| Performed by | Quest |
| Sendout? | Yes |
| Method | Immunoassay |
| Collection Instructions | Time to steady state: 2-3 days. A trough levels is ideally drawn < 1 hour before the next dose. Indicate the time of draw on the requisition. |
| Container type | Red top (Gold top unacceptable), Lavender OK |
| Amount to Collect | 4 mL blood |
| Sample type | Serum (EDTA plasma acceptable) |
| Preferred volume | 1 mL serum or plasma |
| Min. Volume | 0.5 mL serum or plasma |
| UCSF Rejection Criteria | Collected in Gold top (SST). Severely icteric, lipemic or hemolyzed samples |
| Processing notes | Centrifuge and immediately separate serum or plasma specimens from the cells into clean, plastic screw-capped vials. Refrigerate. Order Quest test # 751X . If B/T, order LabCorp #007856 |
| Ref Lab Rejection Criteria | Severely icteric, lipemic or hemolyzed samples |
| Units | mg/L |
| Normal range | Primidone: Therapeutic: 5-15 mg/L Potentially toxic: > 15 mg/L Phenobarbital: 15.0-40.0 mg/L |
| Critical value | UCSF: > 15 mg/L Quest Priority-1: > 15 mg/L |
| Synonyms | Mysoline |
| Stability | Room temperature 3 days, refrigerated 2 weeks, frozen at -20C 1 month |
| Turn around times | Test performed Monday-Saturday. Turnaround time: 1-4 days. |
| Additional information | Assay of Primidone levels is accompanied by the measurement of Primidone's major metabolite Phenobarbital, for which Quest considers the adult therapeutic level to be 10-40 mg/L, the pediatric therapeutic level to be 10-30, and the potentially toxic level to be > 40. Click here for A guide on Drug Level Monitoring |
| CPT coding | 80188-90, 80184-90 |
| LOINC code | 3978-4 |
| Last Updated | 1/23/2013 3:51:14 PM |
| Entry Number | 779 |
If you have additional questions regarding this test, please call: 415-353-1667