UCSF Navigation Bar

UCSF Departments of Pathology & Laboratory Medicine Home Page

Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

Internal Resources

Click here for more information about laboratory operations and procedures

If you have additional questions regarding this test, please call: 415-353-1667

Search Our Test Menu

Paroxysmal Nocturnal Hemoglobinuria Cell Markers

Item Value
Approval req'd? Yes, contact Hematology at x3-1747
Available Stat? No
Test code PNHM
Performed by Mayo
Sendout? Yes
Method Flow cytometry
Container type Lavender top (EDTA)
Amount to Collect 7 mL blood
Sample type Whole blood
Preferred volume 7 mL blood
Min. Volume 3 mL blood
Processing notes Do not transfer sample to another container. Transport at Room temperature to China Basin to Send-outs for pick-up at 1600 hours by Medical Courier.

Order Mayo Medical Labs test code # 81156 (CPT). Send at ambient temperature Monday-Friday, to China Basin Sendouts to meet MAYO Lab courier (MCI) pickup at 1600 hours.

If pickup is missed, ship via Federal Express overnight priority (if shipped on Friday, must check box for Saturday AM delivery) to: Mayo Medical Laboratories, 200 First Street SW, Rochester, MN 55905, Client Services: 800-533-1710

Units % negative
Normal range
Normal ≤ 3% WBC's & RBC's are CD59-
Synonyms PI-linked antigen; PNH; CD55; CD59; ; flow cytometry
Stability Room temperature, 72 hours.
Turn around times Samples accepted Monday-Friday AM only; test run daily. Turnaround time: 2-5 days.
Additional information Flow cytometric immunophenotyping is used to study the leukocyte and RBC surface markers of glycosylphosphatidylinositol (GPI) linked antigens such as CD14 (monocytes) and CD59 (neutrophils and RBC). Fluorescent aerolysin (FLAER), a protein that selectively binds to GPI anchors, is also used in the test. Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) will show abnormality in all or some of these markers to various extents
CPT coding 88180-90 x4
LOINC code 55164-8
Last Updated 11/1/2011 9:48:33 AM
Entry Number 755
UCSF home page UCSF home page About UCSF Search UCSF UCSF Medical Center