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If you have additional questions regarding this test, please call: 415-353-1667
|Clinical Questions||Does my patient have drug-induced thrombocytopenia (including HIT)?|
|Approval req'd?||No, but only run by appointment, Contact Hematology at x3-1747|
|Test group||Platelet function|
|Performed by||Parnassus Hematology|
|In House Availability||Run as needed, Monday - Friday day shift only|
|Patient Preparation||Patient should be rested, fasting since midnight, and no smoking before blood collection. No caffeine and no alcohol for 48 hours prior to testing. Take only medication as directed by physician before testing.|
|Collection Instructions||By appointment only, contact Hematology at x3-1747
Samples are only collected by Hematology techs.
Note:If aggregation testing using less than the full set of agonists is desired, including limited testing for response to aspirin or ADP-receptor antagonists, see "Additional Information" and note specific requests on requisition.
|Container type||Blue tops (x6) and Lavender top|
|Amount to Collect||20 mL blood|
|Sample type||Citrated and EDTA anticoagulated whole blood|
|Preferred volume||20 mL blood|
|Min. Volume||17 mL blood|
|Synonyms||lumi-aggregation; platelet aggregation with luminescence; clopidogrel; plavix; aspirin; ASA|
|Stability||Room temperature 3 hours.|
|Turn around times||1-3 days|
|Additional information|| An interpretation of this test by a laboratory physician will automatically be performed and billed for separately.
Measures the release of ATP in the presence of thrombin, collagen and ATP and examines the aggregation response to Thrombin, ADP, arachidonic acid, collagen, and ristocetin at various concentrations:
A platelet count and pathologist evaluation of platelet morphology on a stained blood smear are required for the performance of this assay and will be ordered and separately charged.
If platelet aggregation is ordered without further specification, a full panel of agonists will be run and interpreted:
- If assessment of clopidogrel response is desired, specify "platelet aggregation for clopidogrel response." A 5 micromolar ADP study will be performed and interpreted.
- If assessment of aspirin response is desired, specify "platelet aggregation for aspirin response." 1 microgram/mL collagen and 5 microgram/mL collagen studies will be performed and interpreted.
- Other combinations of particular agonists can be specifically requested when a full panel of agonists is not needed; conferring with a hematology laboratory physician is requested in this circumstance x3-1747
|Last Updated||3/3/2014 12:02 PM|