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Neutrophil Oxidative Index
|Approval req'd?||Yes, Contact Immunology at x3-1712|
|In House Availability||Monday, Tuesday only (day shift) by appointment. Contact Immunology at x3-1712.|
|Collection Instructions||By appointment only with Immunology, call x3-1712
Sample should be delivered to the laboratory IMMEDIATELY and no later than 1000 on the day of testing. The specimen must reach the Immunology laboratory within FOUR hours of collection.
|Container type||Dark Green top|
|Amount to Collect||6 mL blood|
|Sample type||Heparinized whole blood|
|Preferred volume||6 mL whole blood|
|Min. Volume||3 mL whole blood|
|UCSF Rejection Criteria||Delivered to lab > 30 min after collection or after 1000 hours Monday-Friday|
|Processing notes||Sample must be kept at room temperature and DO NOT centrifuge. Notify Immunology x3-1712 after sample is drawn.|
|Synonyms||NBT;Nitro-blue tetrazolium; CGD; Chronic granulomatous disease; NOI; flow cytometry|
|Turn around times||6-10 days|
|Additional information||This more sensitive assay replaces the NBT test in detecting defects in the generation of peroxide by the monophosphate shunt, and is capable of detecting the carrier state.
The neutrophil oxidative index and the net fluorescence are compared with those of a healthy control and the results are interpreted in a separate report.
This test was developed and its performance characteristics determined by the Clinical Laboratories at the Medical Center at UC San Francisco. It has not been cleared or approved by the U.S. Food and Drug Administration.
|LDT or Mod FDA?||Yes|
|Last Updated||11/27/2012 5:22:08 PM|
If you have additional questions regarding this test, please call: 415-353-1667