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Methylmalonic Acid

Item Value
Clinical Questions Does my patient have anemia due to a nutritional deficiency?
Approval req'd? No
Available Stat? No
Test code MMAS
Test group Methylmalonic
Performed by ARUP
Sendout? Yes
Method Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Container type Gold-top or red-top preferred. Dark green, light green and purple-top acceptable.
Amount to Collect 2.5 mL (blood)
Sample type SERUM
Preferred volume 1.2 mL (serum)
Min. Volume 0.6 mL (serum)
Processing notes Centrifuge and remove serum or plasma from cells within 2 hours of collection. Freeze aliquot and transport to CB frozen. Order ARUP test code 0099431.
Ref Lab Rejection Criteria Room temperature specimens. Grossly hemolyzed or lipemic specimens.
Units umol/L
Normal range 0.00-0.40
Synonyms MMA, Cobalamin Deficiency, Methylmalonate, Vitamin B12 Deficiency
Stability After separation from cells: Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
Turn around times 1-3 days
Additional information MMA levels are determined using liquid chromatography/ tandem mass spectrometry. This test is used for the screening and identification of individuals with B12 (cobalamin) deficiency, and for monitoring patients with one of the inherited forms of methylmalonic acidemia.
CPT coding 83921
LOINC code 13964-2
Last Updated 7/20/2017 11:33:23 AM
Entry Number 659
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