UCSF Navigation Bar

UCSF Departments of Pathology & Laboratory Medicine Home Page

Lab Manual for Moffitt-Long and Mount Zion

Lab Manual for SFGH

Internal Resources

Click here for more information about laboratory operations and procedures

If you have additional questions regarding this test, please call: 415-353-1667

Search Our Test Menu

Metanephrines, 24 hour urine

Item Value
Approval req'd? No
Available Stat? No
Test code METN
Test group Metanephrines
Performed by Quest
Sendout? Yes
Method LC/MS/MS
Patient Preparation Patient should avoid tobacco, tea, coffee, for 3 days prior to specimen collection.

It is preferable for the patient to be off medications for 3 days prior to collection.

Common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. Medications which are alpha agonists (Aldomet), alpha blockers (Dibenzyline) should be avoided 18-24 hrs prior to specimen collection.
Collection Instructions Obtain container from Specimen Receiving.

Refrigerate container during collection
Container type 24 hour urine collection container

Click here for Urine Preservative Requirements
Amount to Collect Entire 24 hour urine output
Sample type 24 hour urine collection
Preferred volume 10 mL urine
Min. Volume 3 mL urine
UCSF Rejection Criteria Container not refrigerated during collection.
Processing notes Add additional 6N HCl if pH > 3. Refrigerate aliquot. Record the patient's age and the total urine volume on the test request form and the transport vial. Order Quest# 19962X for Metanephrines, 24 hour. urine.

If ordered on a random sample order MOLT and request Quest test #14961X for random urine.
Units µg/24 hours (mcg/24 hours)
Normal range Metanephrine
3 months-4 years 25-117 µg/d
5-9 years 11-139 µg/d
10-13 years 51-275 µg/d
14-17 years 40-189 µg/d
18-29 years 25-222 µg/d
30-39 years 36-190 µg/d
40-49 years 58-203 µg/d
≥ 50 years 90-315 µg/d


Normetanephrine
3 months-4 years 54-249 µg/d
5-9 years 31-398 µg/d
10-13 years 67-503 µg/d
14-17 years 69-531 µg/d
18-29 years 40-412 µg/d
30-39 years 35-482 µg/d
40-49 years 88-649 µg/d
≥ 50 years 122-676 µg/d


Metanephrine, Total
3 months-4 years 79-345 µg/d
5-9 years 49-408 µg/d
10-13 years 110-714 µg/d
14-17 years 107-741 µg/d
18-29 years 94-604 µg/d
30-39 years 115-695 µg/d
40-49 years 182-739 µg/d
≥ 50 years 224-832 µg/d
Stability Room temperature 1 week (acidified), refrigerated 8 days, frozen at -20C 1 month
Turn around times Test performed Monday-Friday. Turnaround time: 3-6 days.
Additional information To convert µg/d to nmol/d (SI units) multiply by 5.07 (using MW 197.2).

Creatinine is assayed as a measure of completeness of urine collection. If total creatinine excretion is not within normal limits for the patient's age and sex (see entry for Creatinine) and the patient has normal renal function, the urine collection is probably incomplete and the result is invalid.
CPT coding 83835-90
Last Updated 3/24/2013 7:50:58 PM
Entry Number 654
UCSF home page UCSF home page About UCSF Search UCSF UCSF Medical Center