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|Utilization Guidelines||Manganese performed on whole blood is the preferred method to monitor for toxicity.|
|Patient Preparation||Patient should refrain from taking manganese supplements at least 3 days before collection of sample.|
|Collection Instructions||To avoid contamination, use powderless gloves during phlebotomy.
Transport specimen at on ice.
Mix well, inverting gently 5x.
Click here for detailed instructions for collecting samples for Trace Metals
|Container type||Navy blue top (EDTA) tube|
|Amount to Collect||2 mL blood|
|Sample type||EDTA whole blood|
|Preferred volume||2 mL blood|
|Min. Volume||1 mL blood|
|Processing notes||Follow the detailed processing instructions for Trace Metal Analysis. Refrigerate. Do NOT centrifuge. Do NOT transfer to another container. Order Quest # 4406|
|Normal range||7-19 µg/L|
|Turn around times||Test performed Monday-Friday. Turnaround: 2-5 days.|
|Additional information||Manganese is an essential trace metal. Over 95% of manganese in blood is protein bound and therefore whole blood levels are higher than those derived from serum.
Toxicity that can result from excessive exposure can cause serious organ damage. Symptoms include Parkinsonian-like tremor and gait disturbances. manganese is excreted in bile therefore patients with hepatic dysfunction/cholestasis and receiving manganese in TPN may be at increased risk for toxicity.
To convert µg/L to nmol/L (SI units) multiply by 18.2.
|Last Updated||12/9/2013 2:17:44 PM|