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Lupus Anticoagulant Information
|Processing notes||If "Lupus Anticoagulant" is ordered without further specification, order test package LUPUS which contains RVVTM & HEXA.|
|Synonyms||LA; antiphospholipid AB; Anti-cardiolipin, HEXA; RVVT; Russell's viper venom; Hexagonal phospholipids neutralization|
|Additional information||If "Lupus Anticoagulant" is ordered without further specification, a RVVTM and HEXA will be done.
The Russell's Viper Venom Test and the Hexagonal Phospholipid Neutralization test are 2 tests available to diagnose lupus anticoagulants, which by definition prolong a clotting time, are inhibitors, and are phospholipid dependent.
Lupus anticoagulants along with anti-cardiolipin antibodies and anti-beta-2-glycoprotein antibodies are the three major categories of anti-phospholipid antibodies. If a patient is being evaluated for anti-phospholipid antibody syndrome, the hematology laboratory service at Moffitt-Long recommends that the Anti-phospholipid Antibody Panel (APLA) be performed (as clinically indicated). This panel includes Russell Viper Venom Test (RVVTM), Hexagonal Phospholipid Neutralization Test (HEXA), and Anti-cardiolipin Antibody Tests (ACLG and ACLM), and Anti-beta-2-glycoprotein Antibody Tests (B2GPG and B2GPM).
To monitor unfractionated heparin therapy in the presence of a lupus anticoagulant, Heparin Levels may be needed.
|Last Updated||9/8/2015 8:34:50 AM|