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Lab Manual for Moffitt-Long and Mount Zion

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Lupus Anticoagulant Information

Item Value
Approval req'd? No
Available Stat? No
Test code LUPUS
Test group Anti-phospolipid
Container type
Sample type
Processing notes If "Lupus Anticoagulant" is ordered without further specification, order test package LUPUS which contains RVVTM & HEXA.
Normal range
Synonyms LA; antiphospholipid AB; Anti-cardiolipin, HEXA; RVVT; Russell's viper venom; Hexagonal phospholipids neutralization
Additional information If "Lupus Anticoagulant" is ordered without further specification, a RVVTM and HEXA will be done.

The Russell's Viper Venom Test and the Hexagonal Phospholipid Neutralization test are 2 tests available to diagnose lupus anticoagulants, which by definition prolong a clotting time, are inhibitors, and are phospholipids dependent.

Lupus anticoagulants along with anti-cardiolipin antibodies and anti-beta2glycoprotein antibodies are the three major categories of anti-phospholipid antibodies. If a patient is being evaluated for anti-phospholipid antibody syndrome, the hematology laboratory service at Moffitt-Long recommends that the Antiphospholipid Antibody Panel(APLA) be performed (as clinically indicated). This panel includes Russell Viper Venom Test (RVVTM), Hexagonal Phospholipid Neutralization Test (HEXA), and Anticardiolipin Antibody Tests (ACLG and ACLM), and Anti-beta2glycoprotein Antibody Tests (B2GPG and B2GPM).

To monitor unfractionated heparin therapy in the presence of a lupus anticoagulant, Heparin Levels may be needed.
Last Updated 8/24/2011 12:26:03 PM
Entry Number 629
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