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Leptospira Antibody

Item Value
Approval req'd? No
Available Stat? No
Test code LEPT
Test group Leptispirosis
Performed by ARUP
Sendout? Yes
Method Immunoblot
Container type Gold top or Red top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.1 mL serum
Processing notes Separate serum from cells ASAP or within 2 hours of collection. Freeze aliquot and ship frozen to China Basin

Order ARUP test code 0055233
Ref Lab Rejection Criteria Contaminated, heat-inactivated, hemolyzed, severely lipemic specimens. Any other body fluid.
Normal range
Negative No significant level of Leptospira IgM antibody detected.
Equivocal Questionable presence of Leptospira IgM antibody detected. Repeat testing in 10-14 days may be helpful.
Positive Presence of IgM antibody to Leptospira detected, suggestive of a current or recent infection.
Synonyms Leptospirosis
Stability Room temperature 2 days, refrigerated 2 weeks, frozen at -20C 1 year.
Additional information Samples interpreted as negative indicate that antibody is not present in the sample, or is below the detection level of the method. Since antibodies may not be present during early disease, confirmation two to three weeks later is recommended. An initially-negative result followed by a positive result indicates IgM seroconversion.

Equivocal specimens should be cautiously interpreted. Further testing with an additional specimen is recommended. If the specimen remains equivocal, a second serological method should be considered if leptospirosis infection is still suspected.

Samples interpreted as positive may indicate the specific antibody. Antibody presence alone cannot be used for diagnosis of acute infection, however, because antibodies from prior exposure may circulate for a prolonged period of time.
CPT coding 86720-90
LOINC code 23202-5
Last Updated 2/16/2016 10:17:25 AM
Entry Number 606
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