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Lab Manual for Moffitt-Long and Mount Zion

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Iron, serum

Item Value
Approval req'd? No
Available Stat? Yes
Test code IRON
Test group Iron
Performed by Parnassus Chemistry
In House Availability Test available 24 hours per day 7 days per week
Method Spectrophotometric
Collection Instructions Draw w/o hemolysis, which may artifactually increase the result. To avoid contamination, do not allow the specimen to come into contact with glass.
Container type Gold top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.8 mL serum
Units µg/dL
Normal range
Age Male Female
0 - 6 days 100 - 250 µg/dL 100 - 250 µg/dL
7 days - 11 months 40 - 100 µg/dL 40 - 100 µg/dL
1 - 5 years 22 - 136 µg/dL 22 - 136 µg/dL
6 - 9 years 39 - 136 µg/dL 39 - 136 µg/dL
10 - 13 years 28 - 134 µg/dL 45 - 145 µg/dL
14 - 17 years 34 - 162 µg/dL 28 - 184 µg/dL
≥ 18 years 42 - 175 µg/dL 29 - 189 µg/dL


Note:
1. Normal range for infants 0-1 year adapted from "Fundamentals of Clinical Chemistry" Tietz, 5th edition, 2001.
2. Normal range for children 1-18 years adopted from Soldin, Steven J, "Pediatric Reference Intervals", 6th edition, AACC Press, 2007, method 1.
3. Normal range for adults was determined by testing 271 male and female healthy blood donors at UCSF.
Turn around times Stat 1 hour, Routine 1 day
Additional information To convert µg/dL to µmol/L (SI units) multiply by x 0.179

Gadolinium MR contrast agents including Gadodiamide (Omniscan), Gadoversetamide (Optimark), Gadopentetate Dimeglumine (Magnevist), and Gadoterdiol (Prohance), have been shown to interfere with certain colorimetric assays used in the measurement of various serum cations including iron, magnesium, and calcium.

The UCSF clinical labs utilize a colorimetric assay for the measurement of both serum iron and serum magnesium that are subject to this interference. For serum iron, gadolinium containing agents (Gadodiamide, Gadoversetamide, and Gadopentetate) may produce a falsely low result (on average, 75, 78, and 88% respectively, of the actual iron concentration).

See "Calcium" and "Magnesium" entries for respective interferences.

Reference:Proctor et al. Gadolinium Magnetic Resonance contrast Agents produce Analytic Interference in Multiple Serum Assays. Am J Clin Pathol. 2004;121:282-292.

See also Iron, Transferrin and Saturation of Iron-Binding Capacity
Medical Necessity? Yes. Click here for more information
LOINC code 2498-4
Last Updated 10/22/2013 7:56:34 AM
Entry Number 574
Lab Procedure Link Click here for Procedure
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