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Insulin

Item Value
Test Update Information Method changed from Siemens Centaur XP platform to Abbott Architect i2000 platform on 9/14/2017.

The Architect Insulin calibrators are referenced to the World Health Organization (WHO) Insulin 1st International Reference Preparation, 66/304.

No changes were made to the reference range.
Approval req'd? No
Available Stat? No
Test code INS
Performed by China Basin Chemistry
In House Availability Test available once a week on day shift (Wednesdays)
Method Chemiluminescent Microparticle Immunoassay (Abbott Architect i2000)
Patient Preparation An overnight fast is required prior to specimen collection or reference ranges will not apply.
Container type Gold top or Red top
Amount to Collect 2 mL blood
Sample type Serum
Preferred volume 1 mL serum
Min. Volume 0.150 mL serum
Processing notes Centrifuge promptly. Freeze serum at -20C.
Units mU/L
Normal range
Fasting 3.0 - 19.0 mU/L


Reference range was adopted from ARUP and verified in-house using sample collected by 25 fasting lab donors.

Note: if patient was not fasting, the normal ranges may not apply.

Synonyms Insulin
Stability Stable for 30 days when frozen at -20°C or colder:
Turn around times Test performed Wednesdays.
Additional information
Table 1. Comparison of commercial insulin assays
Roche Elecsys/E170 Architect Immulite 2000 Access Advia Centaur
(Roche Diagnostics, Indianapolis, Indiana) (Abbott Laboratories, Abbott, Illinois) (Siemens Healthcare Diagnostics, Tarrytown, New York) (Beckman Coulter, Fullerton, California) (Siemens Healthcare Diagnostics, Tarrytown, New York)
Human Insulin + + + + +
Aspart - + + + +
Lispro - + + + +
Glulisine - ± - N/A -
Detemir - + - N/A +
Glargine - + + + +
N/A : not available


Source: J Clin Res Pediatr Endocrinol 2014;6(4):258-261
CPT coding 83525
LOINC code 20448-7
Last Updated 9/14/2017 2:27:57 PM
Entry Number 571
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