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IgG Index, CSF

Item Value
Approval req'd? No
Available Stat? No
Test code IGGI and IGGIS
Test group IgG
Performed by Immunology
In House Availability Wednesday (day shift)
Method Rate nephelometry
Collection Instructions Both CSF and serum samples required, preferably collected at the same time. CSF specimen label must contain the date the sample was collected and the legible name of the person who collected the sample.
Container type CSF tube or sterile collection tube and Gold top
Amount to Collect 1 mL CSF AND 1 mL blood
Sample type CSF AND Serum
Preferred volume 0.5 mL CSF AND 0.5 mL serum
UCSF Rejection Criteria Lipemic samples
Processing notes Refrigerate. order IGGI for CSF and IGGIS for serum
Units mg/dL
Normal range
CSF IgG 0.3-4.3 mg/dL
CSF Albumin 5.4-31.8 mg/dL
Serum IgG 672-1760 mg/dL
Serum Albumin (> 10 yer old) 3400-4700 mg/dL
IgG Index, CSF 0.3-0.6
Synonyms Oligoclonal bands; Immunoelectrophoresis, CSF; IFE, CSF
Turn around times 1-8 days
Additional information (Index = (CSF IgG/Albumin)/ (serum IgG/Albumin)

Reference range data applies only to lumbar CSF. A bloody contamination of CSF due to a traumatic LP can significantly elevate the IgG index.

CSF IgG, albumin and index reference ranges from:Tietz Textbook of Clinical Chemistry; 3rd ed., 1999, and Fishman, R.A., Cerebrospinal Fluid in Diseases of the Nervous System; 2nd ed., 1992.

See also Oligoclonal bands.

Immunoelectrophoresis is not offered on CSF.
Last Updated 11/21/2013 12:53:21 PM
Entry Number 560
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