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Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

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If you have additional questions regarding this test, please call: 415-353-1667

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IgE, Specific

Item Value
Approval req'd? No
Available Stat? No
Test code IGES, BTRAST
Performed by ARUP
Sendout? Yes
Method Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
Container type Gold or Red top tube
Amount to Collect 0.5 mL
Sample type Serum
Preferred volume 0.25 mL (plus 0.1 mL per additional allergen ordered)
Min. Volume 0.25 mL (plus 0.04 mL per additional allergen ordered)
Processing notes Refrigerate serum.

Mark the appropriate ARUP test code from the test listing on the reference lab request slip, and order the proper Charge Group of the test in the laboratory computer.

Charge group 1 IGES1
Charge group 2 IGES2
Charge group 3 IGES3
Charge group 4 IGES4
Charge group 5 IGES5

Requests for "Egg Components" should be ordered as: Egg, White; Egg, Whole; Ovomucoid; Ovalbumin

Requests for "Milk Components" should be ordered as: Milk (Cow); Beta-lactoglobulin; Casein; Alpha-lactalbumin

Requests for "Peanut Components" are not covered by this test.

List of Available Allergens
Ref Lab Rejection Criteria Hemolyzed, icteric, or lipemic specimens.
Units kU/L
Normal range <0.10 kU/L
Synonyms RAST
Stability After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Turn around times 2-3 days
Additional information It is generally believed that reactivity of Class 2 or below is not an indication for immunotherapy.

A NEGATIVE RESULT CAN OCCUR IN A SENSITIZED INDIVIDUAL WHO HAS NOT BEEN EXPOSED TO A PARTICULAR ANTIGEN FOR A PROLONGED PERIOD OF TIME, AND MAY ALSO OCCUR IN AN INDIVIDUAL WHO HAS VERY RECENTLY SUFFERED A SEVERE ALLERGIC REACTION.

Due to the rise and fall of circulating antibodies to venoms and to penicillin G or V, specimens should be collected no sooner than 2-3 weeks and no later than 6 months after an insect sting or a penicillin exposure.

List of Available Allergens

Tests must be ordered individually rather than in (more expensive) panels.

Medicare/MediCal will not reimburse testing for specific IgE in a patient who has not previously demonstrated an elevation of total IgE.

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivoreactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.
CPT coding 86003
LOINC code varies
Last Updated 8/31/2017 4:34:28 PM
Entry Number 553
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