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Islet Cell Antibody
|Container type||Red top|
|Amount to Collect||4 mL blood|
|Preferred volume||2 mL serum|
|Min. Volume||0.5 mL serum|
|Processing notes||Order Quest #52654P|
|Stability||Room temperature two days, refrigerated two weeks, frozen at -20C six months.|
|Turn around times||Test performed Monday-Friday (AM). Turnaround 3-5 days|
|Reflex?||Yes, if positive titer will be performed at an additional charge|
|Additional information||Islet cell antibody titer reported in JDF units (Reference Range: less then 1.25 JDF). End point titers are compared to a single international reference standard and values are reported in JDF (Juvenile Diabetes Foundation) units.
Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type I diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.
|Last Updated||10/2/2010 11:52:08 AM|