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Herpes simplex Drug Susceptibility Testing

Item Value
Approval req'd? Yes, consult with Microbiology Director x3-1628
Available Stat? No
Utilization Guidelines This testing should only be ordered on an HSV isolate from an immunocompromised patient with progressing lesions despite full oral or IV dose of the drug. Resistance does not occur in immunocompetent patients and most apparent resistance is due to poor compliance.
Test code P319
Test group Herpes
Performed by Focus Diagnostics
Sendout? Yes
Method Tissue culture
Collection Instructions Specify drugs of interest
Container type
Sample type Viral isolate
Processing notes Clinical isolate (cell culture with 4+ CPE) required. Fill tube with viral maintenance media. Transport overnight at room temperature or transport frozen isolate on dry ice.

Test performed by Focus Diagnostics, 10703 Progress Way, Cypress, CA 90630. Test name: Antiviral Susceptibility. Focus order codes: #53180 (Acyclovir); #53185 (Foscarnet); #53190 (Ganciclovir)
Normal range
Synonyms Drug susceptibility testing; HSV; antiviral susceptability testing
Turn around times 1-2 weeks
Additional information Testing may be appropriate for isolates from patients who have been treated, e.g., with acyclovir or foscarnet, but whose cultures remain positive for Herpes simplex.

Clinical isolate (cell culture with 4+ CPE) required.
CPT coding 87252, 87253
LOINC code 29257-3
Last Updated 6/19/2013 1:24:55 PM
Entry Number 497
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