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Herpes simplex Drug Susceptibility Testing
|Approval req'd?||Yes, consult with Microbiology Director x3-1628|
|Utilization Guidelines||This testing should only be ordered on an HSV isolate from an immunocompromised patient with progressing lesions despite full oral or IV dose of the drug. Resistance does not occur in immunocompetent patients and most apparent resistance is due to poor compliance.|
|Performed by||Focus Diagnostics|
|Collection Instructions||Specify drugs of interest|
|Sample type||Viral isolate|
|Processing notes||Clinical isolate (cell culture with 4+ CPE) required. Fill tube with viral maintenance media. Transport overnight at room temperature or transport frozen isolate on dry ice.
Test performed by Focus Diagnostics, 10703 Progress Way, Cypress, CA 90630. Test name: Antiviral Susceptibility. Focus order codes: #53180 (Acyclovir); #53185 (Foscarnet); #53190 (Ganciclovir)
|Synonyms||Drug susceptibility testing; HSV; antiviral susceptability testing|
|Turn around times||1-2 weeks|
|Additional information||Testing may be appropriate for isolates from patients who have been treated, e.g., with acyclovir or foscarnet, but whose cultures remain positive for Herpes simplex.
Clinical isolate (cell culture with 4+ CPE) required.
|CPT coding||87252, 87253|
|Last Updated||6/19/2013 1:24:55 PM|