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Herpes simplex Drug Susceptibility Testing

Item Value
Approval req'd? Yes, consult with Microbiology Director x3-1628
Available Stat? No
Utilization Guidelines This testing should only be ordered on a body site previously shown to contain HSV from an immunocompromised patient with progressing lesions despite full oral or IV dose of the drug. Resistance does not occur in immunocompetent patients and most apparent resistance is due to poor compliance.
Test code P319
Test group Herpes
Performed by ARUP
Sendout? Yes
Method Cell culture with reflex to phenotypic susceptibilities
Collection Instructions Flocked Swab: Collect fluid of vesicle and rub base of lesion to obtain cells. Please swab in universal transport media.
Fluid/Tissue: Transfer up to 3mL specimen into a sterile container or universal transport media.
Container type Flocked swab/Universal Transport Medium collection kit w/ labeling "For virus testing for sites other than nasopharynx"
Sample type skin lesion swab, vaginal swab, oral swab, tissue, body fluids
Processing notes Dilute body fluids other than CSF and tissues 1:1 in UTM.

ARUP test code 0065065 : HSV Culture w/ Reflex to HSV Typing
Normal range
Synonyms Drug susceptibility testing; HSV; antiviral susceptability testing; Acyclovir; Foscarnet
Turn around times 1-2 weeks
CPT coding 87252, 87253
LOINC code Culture: 16291-7
Acyclovir: 73574-6, 9416-9
Foscarnet: 42317-8
Last Updated 8/11/2017 12:16:44 PM
Entry Number 497
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