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Helicobacter pylori Antigen

Item Value
Approval req'd? No
Available Stat? No
Test code HPAG
Test group H pylori
Performed by UC Irvine
Sendout? Yes
Method EIA
Patient Preparation No prior treatment with antibacterial antibiotics, proton-pump inhibitors or bismuth preparation use for two weeks before samples collection.
Collection Instructions Collect specimens Saturday-Thursday only. Deliver immediately to laboratory. Refrigerate sample if transport is delayed > 1 hour.
Container type Urine cup or other leakproof container
Amount to Collect 1 gm stool
Sample type Unpreserved Stool
Preferred volume 1 gm
Min. Volume 0.5 gm
UCSF Rejection Criteria Watery stools, swabs or specimens in transport media. Samples collected outside of stated time frames.
Processing notes Freeze sample at -20C and transport frozen. Orcer UCI test code SERHPA
Normal range Not detected
Synonyms Campylobacter pyloridis; H pylori; gastritis
Stability Room temperature 1 hour, refrigerated 3 days, frozen 1 month.
Turn around times Performed once per week. Results available in 3-10 days.
Additional information Detection of antigen in the stool is reported to be as sensitive as the urea breath test for the presence of Helicobacter-associated gastritis and nearly as sensitive as PCR (the clinical relevance of the latter is unclear). The presence of antigen cannot be used as a test of cure, as stools remain positive due to persistence of antigen from presumably unviable organisms one month after treatment is initiated in nearly 20% of patients (and in 40% of patients by PCR.
CPT coding 87338- 90
LOINC code 17780-8
Last Updated 12/3/2015 11:44:16 AM
Entry Number 435
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