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Lab Manual for Moffitt-Long and Mount Zion

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Helicobacter pylori Antigen

Item Value
Approval req'd? No
Available Stat? No
Test code HPAG
Performed by UC Irvine
Sendout? Yes
Method EIA
Patient Preparation No prior treatment with antibacterial antibiotics, proton-pump inhibitors or bismuth preparation use for two weeks before samples collection.
Collection Instructions Collect specimens Saturday-Thursday only. Deliver immediately to laboratory. Refrigerate sample if transport is delayed > 1 hour.
Container type Urine cup or other leakproof container
Amount to Collect 1 gm stool
Sample type Unpreserved Stool
Preferred volume 1 gm
Min. Volume 0.5 gm
UCSF Rejection Criteria Watery stools, swabs or specimens in transport media. Samples collected outside of stated time frames.
Processing notes Freeze sample at -20C and transport frozen. Orcer UCI test code SERHPA
Normal range Not detected
Synonyms Campylobacter pyloridis
Stability Room temperature 1 hour, refrigerated 3 days, frozen 1 month.
Turn around times Performed once per week. Results available in 3-10 days.
Additional information Detection of antigen in the stool is reported to be as sensitive as the urea breath test for the presence of Helicobacter-associated gastritis and nearly as sensitive as PCR (the clinical relevance of the latter is unclear). The presence of antigen cannot be used as a test of cure, as stools remain positive due to persistence of antigen from presumably unviable organisms one month after treatment is initiated in nearly 20% of patients (and in 40% of patients by PCR.
CPT coding 87338- 90
LOINC code 17780-8
Last Updated 9/25/2011 7:31:54 PM
Entry Number 435

If you have additional questions regarding this test, please call: 415-353-1667

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