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Gliadin Antibodies (IgG and IgA)
|In House Availability||Friday (day shift)|
|Container type||Gold top|
|Amount to Collect||2 mL blood|
|Preferred volume||1 mL serum|
|Min. Volume||0.5 mL serum|
|Processing notes||Freeze serum at -20°C|
|Normal range|| Gliadin antibody (IgG)
Gliadin Antibody (IgA)
|Synonyms||Celiac disease; gluten sensitive enteropathy; anti deamidated gliadin antibodies|
|Turn around times||2-9 days|
|Additional information||Anti-gliadin antibodies are associated with Celiac Disease (also called gluten-sensitive enteropathy). IgG and/or IgA antibodies can be found, but generally, IgA antibodies are considered more specific for disease, while IgG antibodies are considered more sensitive. This assay uses the deamidated form of gliadin as a substrate, which is considered to have greater diagnostic accuracy in comparison with traditional assays. Testing for antibodies to TTG (tissue transglutaminase) are usually performed in addition to testing for antibodies to gliadin.
Note: Since IgA deficiency is common in patients with celiac disease, serum IgA levels may be useful in patients with negative results for the IgA anti-gliadin assay.
|Last Updated||7/17/2013 9:14:10 AM|