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Gastric Parietal Cell Antibody
| Item | Value | ||||||
|---|---|---|---|---|---|---|---|
| Approval req'd? | No | ||||||
| Available Stat? | No | ||||||
| Test code | GPCA | ||||||
| Performed by | Quest | ||||||
| Sendout? | Yes | ||||||
| Method | ELISA | ||||||
| Container type | Red top | ||||||
| Amount to Collect | 2 mL blood | ||||||
| Sample type | Serum | ||||||
| Preferred volume | 1 mL serum | ||||||
| Min. Volume | 0.3 mL serum | ||||||
| Processing notes | Freeze sample. Order Quest #15114X | ||||||
| Units | Units | ||||||
| Normal range |
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| Synonyms | anti-parietal cell antibody; parietal cell antibodies | ||||||
| Additional information | Pernicious anemia is a chronic disease and is the end stage of type A (autoimmune) chronic atrophic gastritis. The type A chronic atrophic gastritis affects the fundus and body of the stomach, while type B (nonimmune, associated with H. pylori infection) affects the antrum as well as the secretory canaliculi and the tubulovesicles of the gastric parietal cells. This antigen has been identrified as the gastric H+/K+ ATPase (gastric proton pump). GPA bind to both the alpha and beta subunits of the H+/K+ ATPase. GPA prevalence increases with age and has been reported in 2.5% of a normal population 30-39 years old and in 9.6% of a population in their 8th decade. |
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| LOINC code | 56147-2 | ||||||
| Last Updated | 10/2/2010 11:51:55 AM | ||||||
| Entry Number | 415 |
If you have additional questions regarding this test, please call: 415-353-1667