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Fetal Fibronectin

Item Value
Approval req'd? Yes, contact Chemistry at x3-1501 if Stat testing is desired
Available Stat? Yes
Test code FFN
Performed by Parnassus Chemistry
In House Availability Test available 24 hours per day 7 days per week
Method Immunoassay (Adeza TLi)

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Patient Preparation Patient specimens should not be tested if the patient has had sexual intercourse within 24 hours prior to sampling time.
Collection Instructions Specimens should be obtained prior to collection of culture specimens, digital cervical examination or vaginal probe by ultrasound examination,as manipulation of the cervix may cause the release of fetal fibronectin.

Care must be taken not to contaminate the Dacron collection swab or cervicovaginal secretions with lubricants, soaps, disinfectants or creams.

Fetal fibronectin tests are not intended for use in women with moderate or gross vaginal bleeding, known placental abruption, or placental previa.

Once the specimen is collected, store the collection tube and sample at 4C and transport to laboratory within 24 hours of collection.
Container type Special container with holding medium for dacron swab (available from lab x3-1501). The collection tube and swab should be stored at room temperature.
Sample type Vaginal fluid
UCSF Rejection Criteria Delivered to lab > 24 hours after collection
Processing notes The collection tube and swab should be stored at room temperature.
Normal range Negative
Synonyms FFN; fibronectin, fetal
Stability Refrigerated 3 days, frozen at -20C 3 months
Turn around times 4 hours
Additional information Detection of fetal fibronectin in cervico-vaginal secretions is associated with preterm delivery in symptomatic pregnant women between 24 weeks and 34 weeks, 6 days gestation and in assymptomatic pregnant women 22 weeks to 30 weeks, 6 days gestation.

Specimens should be obtained prior to collection of culture specimens, digital cervical examination or vaginal probe by ultrasound examination, as manipulation of the cervix may cause the release of fetal fibronectin.

Fetal fibronectin tests are not intended for use in women with moderate or gross vaginal bleeding, known placental abruption, or placental previa.

Call x3-1501 when more collection tubes and swabs are needed; allow at least 24 hours for delivery of collection kits.
LOINC code 20404-0
Last Updated 10/2/2010 11:51:52 AM
Entry Number 386
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