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If you have additional questions regarding this test, please call: 415-353-1667
|Clinical Questions||Does my patient have hemophagocytic lymphohistiocytosis?
Does my patient have thalassemia?
Does my patient have anemia due to a nutritional deficiency?
Does my patient have hemochromatosis?
|Approval req'd?||For testing outside of normal test availability (e.g. weekend testing) contact Laboratory resident on-call at x3-1667|
|Performed by||China Basin Chemistry|
|In House Availability||Monday-Friday (day shift)|
|Method||Chemiluminescent immunoassay (Siemens Centaur)|
|Container type||Gold top (preferred). Red or Lt. Green top acceptable|
|Amount to Collect||1 mL blood|
|Sample type||Serum (preferred) or Heparinized plasma|
|Preferred volume||0.5 mL serum or plasma|
|Min. Volume||0.25 mL serum or plasma|
Reference ranges adopted from Quest Diagnostics based on split Pt. comparison testing using the same instrument/methodology (Siemens Centaur)
|Turn around times||1-3 days|
|Additional information||Hemolyzed specimens may give false elevations. Our reference range does not differentiate menstruating and non-menstruating females, but levels are known to approach those in males following menopause.
Ferritin is a more sensitive test of iron stores than serum iron, transferrin saturation (saturation of iron-binding capacity) or RBC indices. Iron-deficient erythropoiesis begins at ferritin levels of 25-40 µg/L, within the reference range; a cutoff level of 16 yields a sensitivity of 75% and a specificity of 98% (Hallberg L et al. Br J Haematol 1993;85:787).
Markedly elevated levels may be seen in some infections, in hemochromatosis, in patients with repeated red cell transfusions (e.g. thalassemia) and in Hemophagocytic Lymphohistiocytosis (HLH)
|Medical Necessity?||Yes. Click here for more information|
|Last Updated||5/1/2011 5:54:49 PM|
|Lab Procedure Link||Click here for Procedure|