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Lab Manual for Moffitt-Long and Mount Zion

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Factor Inhibitor Screen

Item Value
Approval req'd? Yes, contact Hematology, x3-1747.
Available Stat? No
Test code INHB
Test group Factor Inhibitor Screen
Performed by Parnassus Hematology
In House Availability Test run 0800-1500 Monday-Friday
Collection Instructions Specify whether Factor Inhibitor Screen is being requested on PT or PTT. Factor Inhibitor Screen on PT will be performed only if PT > 18 seconds. Factor Inhibitor Screen on PTT will be performed only if PTT > 33.7 seconds. If test is ordered on samples with shorter clotting times, the inhibitor screen cannot yield a positive result; "test not indicated" will be sent.

1. Check the expiration date on the label of the blue top vacutainer before drawing the patient.

2. For blood collection in a sodium citrate blue top, the tube must be filled to above the Minimum Fill Indicator on the tube. It is crucial to wait and allow the tube to stop filling before removing it from the needle.

3. With use of a butterfly needle, draw about 1 cc using a separate blue top to remove air from tubing, discard the first tube and then draw a second blue top tube filled to the full extent of the vacuum.

4. Tubes should not be filled past the Maximum Fill dashed line by either using a syringe or removing the tube cap.

Deliver immediately to the laboratory.

For patients with Hct's ≥ 55% please contact Hematology (x3-1747) to obtain blue top tubes with adjusted citrate volumes in order to maintain the proper citrate to plasma ratio for coagulation studies.
Container type Blue top filled to full extent of vacuum x3
Amount to Collect 8 mL blood
Sample type Citrated plasma
Preferred volume 4 mL plasma
Min. Volume 3 mL plasma
UCSF Rejection Criteria Samples collected in outdated blue top vacutainer. Over-filled or under-filled tubes may be rejected
Processing notes Freeze in plastic at -20C.
Normal range Negative
Synonyms Circulating anticoagulant; Factor VIII inhibitor; Factor IX inhibitor; Porcine factor VIII inhibitor screen; F8 inhibitor; F9 inhibitor; mixing study
Turn around times Same day or next weekday
Additional information Specify whether Factor Inhibitor Screen is being requested on PT or PTT. Factor Inhibitor Screen on PT will be performed only if PT > 18 seconds. Factor Inhibitor Screen on PTT will be performed only if PTT > 33.7 seconds. If test is ordered on samples with shorter clotting times, the inhibitor screen cannot yield a positive result; "test not indicated" will be sent.

Collecting three tubes assures that enough specimen is available if the Factor Inhibitor Titer must be performed in addition to the Factor Inhibitor Screen.
LOINC code 40744-5
LDT or Mod FDA? Yes
Last Updated 11/27/2012 5:20:47 PM
Entry Number 355

If you have additional questions regarding this test, please call: 415-353-1667

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