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Disaccharidases

Item Value
Approval req'd? No
Available Stat? No
Test code DSCS
Performed by Quest
Sendout? Yes
Method Spectrometry
Collection Instructions Do not place tissue on gauze or filter paper; do not add saline or allow contact with support, preservatives or embedding material.

Transport immediately to laboratory.
Container type Small bowel biopsy
Amount to Collect 5 mg
Sample type Small bowel biopsy
Preferred volume 5 mg
Min. Volume 2 mg
UCSF Rejection Criteria Sample submitted improperly. Delivered to laboratory > 30 minutes after collection
Processing notes Specimen must be kept frozen and stored at -70C. Do not thaw. Deliver to China Basin on dry ice.
Units µM glucose generated/min/ g protein
Normal range
Lactase 15.0-45.5 µM gluc/min/g prot
Maltase 25-69.9 µM gluc/min/g prot
Palatinase 100-224.4 µM gluc/min/g prot
Sucrase 5-26.3 µM gluc/min/g prot
Synonyms Lactase deficiency; palatinase deficiency; sucrase deficiency; maltase deficiency
Additional information Lactase, maltase, palatinase and sucrase are mucosal disaccharidases that are present in normal small intestine and fetal colon. A decrease in the enzyme activity of these disaccharidases has been noted in colonic adenomas, adenocarcinomas and malabsorption. Decreased disaccharidase activity is a good indication of mucosal injury with the exception of lactase.
CPT coding 84311-90 x4
LOINC code 1942-2
Last Updated 11/5/2012 12:53:09 PM
Entry Number 311
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