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Lab Manual for Moffitt-Long and Mount Zion

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Cytomegalovirus DNA, Quantitative, Non-blood samples

Item Value
Approval req'd? None required for CSF, amniotic fluid and urine testing. Requests for testing on all other non-blood samples require approval, contact Microbiology @ x31268. (see Additional Information)
Available Stat? No
Test code CMVMIS
Test group CMV
Performed by Viracor
Sendout? Yes
Method Quantitative Real-time PCR
Container type CSF tube or sterile collection tube, EDTA Tube, Urine cup
Amount to Collect 3 mL CSF or fluid
Sample type CSF, Bone marrow, Unfixed tissue, BAL, Amniotic fluid, Urine
Preferred volume 3 mL CSF or fluid
Min. Volume 2 mL CSF or fluid
Processing notes Freeze samples and ship frozen to China Basin. Ship on dry ice to Viracor.
Units IU/mL
Normal range Not detected
Synonyms CMV; PCR; CID; CMV inclusion disease
Turn around times Test run Monday-Saturday, results available 24 hours after receipt by ViraCor.
Additional information Clinical Significance: CMV infections are common and usually asymptomatic.In patients who are immunocompromised, CMV may cause disseminated, severe disease. CMV may cause birth defects in a minority of infected newborns. DNA methods provide the highest sensitivity and specificity of any method.

For detection of CMV in congenital infection, qualitative CMV culture of urine has adequate sensitivity and better specificity than PCR, which can be too sensitive and pick up very low levels of virus. While CMV PCR on urine from immunocompromised patients has a fairly low specificity for disease, there is some literature describing utility of quantitative CMV PCR on urine for following renal transplant patients.
LOINC code 33006-8
Last Updated 12/16/2013 11:04:37 AM
Entry Number 291

If you have additional questions regarding this test, please call: 415-353-1667

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