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Cutaneous Antibodies
| Item | Value |
|---|---|
| Approval req'd? | No |
| Available Stat? | No |
| Test code | No test code, see Processing instructions |
| Performed by | UCSF IF Lab |
| Sendout? | Yes |
| In House Availability | Daily, Monday-Friday |
| Method | Indirect immunofluorescence |
| Collection Instructions | Complete Dermatopathology requisition and submit with sample. Samples should be received by the laboratory by Wednesday for next Monday signout. |
| Container type | Gold top |
| Amount to Collect | 4 mL blood |
| Sample type | Serum |
| Preferred volume | 2 mL serum |
| Min. Volume | 1 mL serum |
| Processing notes | Store and transport at room temperature. Send sample and completed dermatopathology requisition to: UCSF Dermatopathology office, Mount Zion Campus, 1701 Divisadero St., 3rd floor Room 350, San Francisco, CA 94115. For questions contact the UCSF Immunofluorescence Lab at 353-7546. |
| Units | titer |
| Normal range | Negative titer < 1:10 |
| Synonyms | Blistering diseases; blistering disorders; BMZ antibodies; Bullous disease; Cutaneous immunofluorescent antibodies; basement membrane antibodies; epidermolysis bullosa aquisita; fluorescent antibodies for bullous disease; Pemphigoid; pemphigus |
| Turn around times | 3-5 days |
| Additional information | Identifies the presence of serum antibodies against intercellular substance in squamous epithelium (pemphigus vulgaris) or basement membrane (bullous pemphigoid). Nuclear staining may be seen from sera of patients with systemic lupus or other connective tissue disorders. Antibodies are typically present during active disease. If positive, it is advisable to perform direct immunofluorescent testing on biopsies of skin lesions. A two-fold drop in titer is indicative of effective therapy. |
| Last Updated | 5/22/2013 2:12:25 PM |
| Entry Number | 281 |
If you have additional questions regarding this test, please call: 415-353-1667