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Anti-Phospholipid Antibody Panel

Item Value
Clinical Questions Does my patient have antiphospholipid syndrome (APLS)?
Approval req'd? No
Available Stat? No
Test code APLA
Test group Anti-phospholipid
Performed by Parnassus Hematology, Immunology
Collection Instructions Check the expiration date on the label of the blue top vacutainer before drawing the patient

Fill 2 Blue tops to full extent of vacuum, Gold top (or Red top) must contain at least 2 mL blood.

For patients with Hct's ≥ 55% please contact Hematology (Parnassus: 3-1747, Mission Bay 6-1094) to obtain blue top tubes with adjusted citrate volumes in order to maintain the proper citrate to plasma ratio for coagulation studies.
Container type Blue tops filled to full extent of vacuum x 2 and Gold top x1 (Red top acceptable)
Amount to Collect Two full Blue tops AND 2 mL blood in Gold top (Red top acceptable)
Sample type Citrated plasma AND serum
Preferred volume 2 mL citrated plasma AND 1 mL serum
Min. Volume 1 mL citrated plasma AND 0.6 mL serum
UCSF Rejection Criteria Samples collected in outdated blue top vacutainer.
Processing notes If "Anti-phospholipid Antibody" is ordered without further specification, order the Anti-phospholipid Panel (APLA).

Panel contains the following test codes: RVVTM, HEXA, ACLM, ACLG, B2GPG, B2GPM
Normal range
Synonyms LA; Lupus anticoagulant; antiphospholipid syndrome
Additional information Panel includes Russell's Viper Venom Test (RVVTM), Lupus Anticoagulant by HEXA (HEXA), Anticardiolipin Antibodies IgG & IgM (ACLG, ACLM), and Beta 2 Glycoprotein Antibodies IgG & IgM (B2GPG, B2GPM). If "Anti-phospholipid Antibody" is ordered without further specification, the Anti-phospholipid Panel will be performed.

Lupus anticoagulants, along with anti-cardiolipin antibodies and anti-Beta 2 Glycoprotein antibodies, are the major categories of anti-phospholipid antibodies. If a patient is being evaluated for anti-phospholipid antibody syndrome, the hematology laboratory service at Moffitt-Long recommends that the Russell's Viper Venom Test, Lupus Anticoagulant by HEXA, Anticardiolipin Antibodies IgG & IgM , and anti- Beta 2 Glycoprotein Antibodies IgG & IgM, each be performed as clinically indicated.
CPT coding 86147
LOINC code 55395-8
Last Updated 5/28/2016 6:34:34 PM
Entry Number 27
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