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Lab Manual for Moffitt-Long and Mount Zion

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Cortisol, Unconjugated, urine

Item Value
Approval req'd? No
Available Stat? No
Test code CRTF
Test group Cortisol
Performed by Quest
Sendout? Yes
Method Tandem Mass Spectrometry
Collection Instructions Obtain container from Specimen Receiving. Report any medications that the patient is taking.
Container type 24 hour urine collection container

Click here for Urine Preservative Requirements
Amount to Collect Entire 24 hour urine output
Sample type 24 hour urine collection
Preferred volume 2 mL urine
Min. Volume 0.5 mL urine
Processing notes Freeze aliquot from well mixed collection at -20C. Include any information regarding medication the patient is taking. Order Quest # 11280X.
Units µg/24 hours (mcg/24 hours)
Normal range
< 1 year old Not established
1-4 years old 0.9-8.2 µg/24 hours
5-9 years old 1.0-30.0 µg/24 hours
10-13 years old 1.0-45.0 µg/24 hours
14-17 years old 3.0-55.0 µg/24 hours
≥ 18 years old 4.0-50.0 ug/24 hours
Synonyms Free cortisol; Cortisol, free; Free F; Free hydroxycorticoids
Turn around times Test performed Monday-Saturday. Turnaround time: 2-5 days.
Additional information To convert µg/d to nmol/d (SI units) multiply by 2.76.

Urinary creatinine is assayed as a measure of the completeness of urine collection. If the total creatinine excretion is not within normal limits for the patient's age and sex (see entry for Creatinine) and the patient has normal renal function, the urine collection is probably incomplete and the result is invalid.

Because of cyclical excretion and problems with urine collection, it is recommended that assays be repeated on at least two consecutive 24 hour samples: "normalization" of excretion per gram of urinary creatinine cannot correct for incomplete collection (Orth, DN. NewEngl J Med. 1995; 332:791).
LOINC code 2147-7
Last Updated 3/24/2013 7:48:09 PM
Entry Number 259

If you have additional questions regarding this test, please call: 415-353-1667

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