UCSF Navigation Bar

UCSF Departments of Pathology & Laboratory Medicine Home Page

Lab Manual for UCSF Clinical Laboratories

Lab Manual for SFGH

Internal Resources

Click here for more information about laboratory operations and procedures

If you have additional questions regarding this test, please call: 415-353-1667

Search Our Test Menu

Copper, 24 hour urine

Item Value
Approval req'd? No
Available Stat? No
Test code COPU
Test group Copper
Performed by Quest
Sendout? Yes
Method ICP/MS
Collection Instructions Click here for detailed instructions for collecting samples for Trace Metals
Container type Acid washed 24 hour urine collection container

Click here for Urine Preservative Requirements
Amount to Collect Entire 24 hour urine output
Sample type 24 hour urine collection
Preferred volume 7 mL urine
Min. Volume 3 mL urine
Processing notes Follow the detailed processing instructions for Trace Metal Analysis.

Record total volume of urine received and write on request. Be sure the urine is mixed well before transferring to the shipping container. To avoid contamination, carefully pour the designated amount of urine directly from the collection container into the acid wash shipping container.

Prepare two (2) aliquots, save (1) for storage, discard after 1 week. Refrigerate aliquots.

For 24 hour urine Order Quest # 365. For random urine order Quest # 86579N
Ref Lab Rejection Criteria Hemolysis or fecal contamination.
Units µg/24 hours
Normal range 15-60 µg/24 hours
Synonyms Cu; Wilson's disease; Menke's disease
Stability Room temperature 5 days, refrigerated 2 weeks, frozen at -20C 1 month.
Turn around times Test run Tuesday-Saturday. Turnaround time: 2-5 days.
Additional information To convert µg/L to µmol/L (SI units), multiply by 0.0157.

Levels are high in most symptomatic patients but false-positive results can occur in obstructive liver disease.

Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chelation therapy.
CPT coding 82525-90
LOINC code 5633-3
Last Updated 6/21/2016 08:15:07
Entry Number 257
UCSF home page UCSF home page About UCSF Search UCSF UCSF Medical Center