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Clomipramine
| Item | Value | ||||||
|---|---|---|---|---|---|---|---|
| Approval req'd? | No | ||||||
| Available Stat? | No | ||||||
| Test code | CLMP | ||||||
| Performed by | Quest | ||||||
| Sendout? | Yes | ||||||
| Method | Liquid Chromatography Tandem Mass Spectrometry | ||||||
| Collection Instructions | Do NOT use serum separator tube. Optimum time to sample is 12-14 hours after oral dose. |
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| Container type | Red top (Gold top unacceptable) | ||||||
| Amount to Collect | 6 mL blood | ||||||
| Sample type | Serum | ||||||
| Preferred volume | 3 mL serum | ||||||
| Min. Volume | 1.5 mL serum | ||||||
| UCSF Rejection Criteria | Sample collected in Gold top | ||||||
| Processing notes | Separate and refrigerate serum as soon as possible. | ||||||
| Units | µg/L (mcg/L) | ||||||
| Normal range |
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| Critical value | Quest Priority-1: ≥ 600 µg/L | ||||||
| Synonyms | Anafranil | ||||||
| Stability | Room temperature 1 hour, refrigerated 5 days, frozen at -20C 1 month. | ||||||
| Turn around times | Test run Wednesday. Turnaround time: 3-8 days. | ||||||
| Additional information | Includes desmethyl metabolite. Neuroleptic drugs cause increased N-Desmethyl Clomipramine. There is great variability of N-Desmethyl Clomipramine to Clomipramine ratio of approximately 2-6:1. The above ranges are a consensus of several publications. The distribution of individual patient concentrations is not normal. The most common side effects are dry mouth, somnolence, and tremor. |
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| CPT coding | 83789-90 | ||||||
| LOINC code | 3491-8 | ||||||
| Last Updated | 7/31/2012 4:14:44 PM | ||||||
| Entry Number | 218 |
If you have additional questions regarding this test, please call: 415-353-1667