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Lab Manual for Moffitt-Long and Mount Zion

Lab Manual for SFGH

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Chloride, sweat

Item Value
Approval req'd? No
Available Stat? No
Test code SWCL
Test group Chloride
Performed by China Basin Chemistry
In House Availability Monday-Friday (day shift)
Method Chloridometer - coulometric titration
Collection Instructions By appointment only: call the Neonatal Clinical Physiology Laboratory, 353-1755 from 0900-1700 hours, Monday-Friday. (see Notes)
Container type
Amount to Collect See preferred volume
Sample type Sweat
Preferred volume At least 15 µL sweat, collected by NCPL lab personnel
Processing notes Deliver sample to Chemistry China Basin same day sample is collected.
Units mmol/L
Normal range For infants up to and including 6 months of age:
CF unlikely < 30 mmol/L,
Intermediate 30-59 mmol/L,
Indicative of CF ≥ 60 mmol/L.


For individuals older than 6 months of age:
CF unlikely < 40 mmol/L,
Intermediate 40-59 mmol/L,
Indicative of CF ≥ 60 mmol/L.


Reference ranges adopted from:
Farrell PM, et al. Guidelines for diagnosis of cystic fibrosis in newborns through older adults: Cystic Fibrosis Foundation consensus report. J Pediatr 2008;153:S4-S14
Synonyms Cl; Sodium, sweat; Cl-; cystic fibrosis; CF
Turn around times 1-3 days
Additional information Outpatient testing is done in the Ambulatory Care Center (ACC) pediatric phlebotomy station, A 220. Patients should arrive prior to the scheduled time to allow for registration, and should bring a written request from the ordering physician. Requisitions may be delivered or mailed to the ACC Pediatric Laboratory (Box 0100, A 220) ahead of time. The test lasts about one hour, during which time the patient should remain near the laboratory to check upon the progress of the test.

The laboratory usually schedules one patient per day. Calls to schedule same-day testing are acceptable but depend on the lab staff availability. A scheduled appointment may be delayed if the laboratory has to provide urgent services to ICN or LDR patients prior to the time of the appointment. Such delays will be notified as soon as possible to the outpatient upon arrival or the inpatient's caregiver (physician or nurse). Sweat chlorides can be performed only between 8:00 and 11:30 a.m., Monday through Friday. When scheduling 11:30 appointments, please request unit to remind outpatients to be on time.

Sodium measurement on sweat is not offered
LOINC code 2077-6
Last Updated 8/24/2011 12:17:51 PM
Entry Number 189

If you have additional questions regarding this test, please call: 415-353-1667

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