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Carcinoembryonic Antigen

Item Value
Approval req'd? No
Available Stat? No
Test code CEA
Test group Carcinoembryonic Antigen
Performed by China Basin Chemistry
In House Availability Monday, Wednesday, Friday (day shift)
Method Chemiluminescent Immunoassay (Siemens Centaur)
Container type Gold top
Amount to Collect 1 mL blood
Sample type Serum
Preferred volume 0.5 mL serum
Min. Volume 0.25 mL serum
Processing notes Centrifuge and freeze at -20C.
Units µg/L
Normal range < 3.8 µg/L
Synonyms CEA
Turn around times 1-4 days
Additional information "Normal" values do not exclude a malignant disorder, while values can often be elevated in normal individuals. In a group of normal non-smokers (1045) and smokers (560), the distribution of results was:

Level Non-smokers Smokers
0- 3.0 µg/L 93.4% 81.2%
3.1- 5.0 µg/L 5.6% 15.0%
5.1-10.0 µg/L 0.9% 3.8%
> 10.0 µg/L 0.1% None

The test contributes little in following patients for recurrence after colon cancer, with an overall sensitivity of 59% and a specificity of 84%. Sensitivity was highest (76-78%) for essentially unsalvageable patients with liver metastasis, but low (29-45%) for patients with only local recurrence (Moertel CG et al. JAMA 1993;270:943).
CPT coding 82378
LOINC code 2039-6
Last Updated 5/29/2016 8:33:52 PM
Entry Number 176
Lab Procedure Link Click here for Procedure
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